ADAM17 fluorometric drug discovery Kit

Cat.No. :
Kit-0048
Size :
96 wells
Description :
The ADAM17 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide: Mca-PLAQAV-Dpa-RSSSR-NH2. Mca fluorescence is quenched by the Dpa group until cleavage by proteases separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of ADAM17, a potential therapeutic target. The compound GM6001 is also included as a prototypic control inhibitor.
Applications :
Designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide.
Storage :
-80°C
Kit Components :
1 vial ADAM17 enzyme1 vial Substrate (Mca-PLAQAV-Dpa-RSSSR-NH2)1 vial DMSO1 vial CALIBRATION STANDARD1 vial control inhibitor1 bottle (20 ml) assay buffer1 black 96-well microplate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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