Nature: “Reconstruct” T cells into the Brain and Attack “Escape” Cancer Cells

For glioblastoma, immunotherapy faces a particular challenge—the blood-brain barrier blocks T cells from entering the brain to prevent brain inflammation that can be life-threatening. This “protective measure” is beneficial under normal conditions, but it prevents T cells from reaching the glioblastoma, leaving immunotherapy useless.   On September 5th, Nature published an article entitled “A homing system targets therapeutic T cells to brain cancer”, which reveals a new solution from a…

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