The last post has given an introduction to liquid biopsy and its first four applications. This post is to analyze this rest four: Cancer Treatment Last year, some companies began to establish genetic map of cancer through mutated DNA fragments found in the blood. This “diagnosis and treatment” test can be used to determine which medication is suitable for the patients because cancer is caused by a specific mutation and…
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Eight Applications of Liquid Biopsy (Part One)
Liquid Biopsy, one of the hottest words recently, has been selected as on of the 2015 Top Ten Breakthrough Technology by MIT Technology Review. Years before, it’s only limited to researches, but now it is more frequently used in clinical. Liquid Biopsy, in fact, is to determine the human blood floating DNA fragments using high-speed sequencing. When a person’s body has exogenous DNA, such as infants, cancer or organ transplant,…
Who Will Win The 2015 Nobel Prize in Physiology or Medicine?
As it’s approaching to the Nobel Prize month, SCI certainly will make forecast by citation. However, the accuracy is not that satisfactory. Typically, the Nobel Prize mainly rely on the peer recommendation, thus hot and mature areas might win. And since the announcement day for the 2015 Nobel Prize Physiology or Medicine is only 20 days left, the writer would like to make a prediction of it. What technologies might…
Novel Explanation for “Runner’s High”
Running is a pleasant thing. And the happiness, freedom and the feeling of energetic is never just owing to the function of endorphin. A recent study published on Cell Metabolism suggested that dopamine, an important neurotransmitter, has influence on this so-called “runner’s high” too. The researchers pointed out that this “reward effect” in exercise is under the regulation of leptin, which can inhibit the body’s physical activity through dopamine…
Why Human Beings Are Called the Lord of Creation?
Why human beings are the most intelligent animals on the planet? Researchers at the University of Toronto gave an answer to it these days. This owes to a key molecular events. Studies have shown that a small change of PTBP1 protein controls the generation of neurons, helping mammals to evolve larger and more complicated brains. The size and complexity of the brain of vertebrates has significant difference. For example, humans…
Cell launched Four Featured Cancer Immunotherapy Reviews
Although it has been years since the idea of using immune system to fight against cancer come into being, only until recent years do scientists find some successful treatment strategies. By manipulating the immune checkpoints and T cell activation to exert anti-tumor activity, immunotherapy has been applied to a wider range of malignancies now, while it only showed therapeutic potential in several types of cancers in the very beginning. Recently…
Obesity? Novel Gene Accounted for That Was Found!
Recently, a research paper published in Nature Communications, has claimed that a key gene that leads to obesity was found. The genes presents in all cells of the body, and it can encode a protein called 14-3-3ζ. The researchers pointed that when silencing the expression of gene in the mouse body, a special type of unhealthy white fat in the mice body would decrease by 50%. This kind of fat…
Regeneration of Heart?
In all one’s life, the blood, hair and skin cells can be continuously regenerated, but the heart cells lose proliferative capacity soon after birth. UCLA researchers first clarified the reasons why adult heart can not regenerate. The study, published in a recently Journal of Cell Biology, could help people reprogram the patient’s heart, so that Cardiomyocytes cells can regain the ability to repair itself. In the first week after birth,…
What’s Your Body Posture During Sleep?
First, question asked. What’s your posture during your sleep? Lying On Side, Lying Flat or Lying On Front? New study results have shown that lying on one’s side may help prevent Alzheimer disease. A report on the Journal of Neuroscience claimed that compared to lying flat and lying on one’s front, lying on one’s side can more efficiently remove the waste of the brain. And this posture was also proven…
Dog Sniffs Cancer, Do You Believe It?
Dogs can help sniff cancer, though sounds incredible, this research has made a huge steep forward these years. Today, the “Cancer sniffing dogs project” has been approved by British NHS, entering into the testing phase, in order to further validate this uncanny ability of dogs. Actually, the ability of dogs to smell cancer is well documented. A 1989 report marked the first medical record of this ability. And the following…