In a new study, researchers from the Will Cornell Medical Center, Memorial Sloan Kettering Cancer Center, and Columbia University’s Wagros School of Internal and External Medicine pointed out that the coronavirus SARS-CoV-2, which causes COVID-19, can infect dopaminergic neurons in the brain and cause aging, meaning they lose their ability to grow and divide. They believe that further research on this discovery may reveal neurological symptoms related to long-term COVID-19,…
SARS-COV-2
PLSCR1 Is a Cellular Autonomous Defense Factor That Resists SARS-Cov-2 Infection
Earlier this month, multiple health departments confirmed that BA.2.86- a highly mutated SARS-CoV-2 virus that causes COVID-19- poses a risk of rapid transmission in countries around the world. This week, the latest vaccination plan will be launched across the United States, but it remains to be seen whether this latest vaccination plan will effectively slow down the spread of BA.2.86 or other new virus variants. However, vaccines remain the…
Occluding the ACE2 receptor, renders all mutants incapable of infection!
With successive waves of uncapping, enhancing disease resistance has become one of the most important things at present. Vaccines are the most effective medicines to fight the coronavirus at the moment, and intensified vaccination is also a more desirable method. However, the Omicron virus strain has evolved an extreme ability to infect, and it is not realistic to hope for a vaccine to eliminate the infection. On the other…
Inhibition of TMEM16 Can Effectively Block the Production of Syncytia Induced by SARS-CoV-2 Infection
Since the outbreak of COVID-19, it still seriously affects our lives. Therefore, the research on the pathogenesis of COVID19 and the development of related drugs will help to alleviate the epidemic situation and help to make our lives return to normal as soon as possible. Previous studies have shown that COVID19 is a disease with unique characteristics, including pulmonary thrombosis, frequent diarrhea, abnormal activation of inflammatory response and alveolar edema,…
Smokers Express Higher ACE2 and Are Susceptible to Coronavirus Infection
Data from COVID-19 patients indicate that smokers are at higher risk of complications. The researchers published an article in the journal Developmental Cell that one of the possible reasons is that smoking increases the gene expression of ACE2 (a protein that binds to SARS-CoV-2), which may promote COVID- 19 infections. The study shows that long-term smoking will increase the ACE2 protein in the lungs, which may lead to a higher…
Study Found the Global SARS-CoV-2 Is Composed of Six Main Subtypes
The World Health Organization announced the global pandemic of COVID-19 in March 2020, the second pandemic in the 21st century. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA beta coronavirus of the Coronaviridae family. The expansion of virus populations, such as SARS-CoV-2, has accumulated many shared polymorphisms, which has caused confusion in traditional clustering methods. In this case, a method to reduce the complexity of the sequence space…
Why SARS-CoV-2 Spread So Easily Among People?
Researchers have identified microscopic features that may make this pathogen more infectious than the SARS virus and can serve as drug targets. With nearly 100,000 people infected with SARS-CoV-2 worldwide, researchers are racing to understand what makes it so easy to spread. Several genetic and structural analyses have identified a key feature of this virus—a protein on the surface—which may explain why it is so susceptible to infect…
Nature: Scientists are Developing Nanovaccines to Fight New Crown Viruses
As infections from SARS-CoV-2 spread from Wuhan, China, to all over the world, researchers are scrambling to develop a vaccine, and life science companies are providing help. On January 28, 2020, a few weeks after the first official report of the first case of coronavirus in 2019, the U.S. Department of Health and Human Services held a press conference in Washington, D.C., saying that SARS-CoV-2 infected thousands of people…