In a new study, researchers from the Will Cornell School of Medicine in the United States have developed an innovative human neuron model that can effectively simulate the diffusion of tau protein aggregates in the brain – a process that is responsible for cognitive decline in Alzheimer’s disease and frontotemporal dementia. Through this new model, they discovered novel therapeutic targets that may prevent tau diffusion. This preclinical study is a…
Tau
Cryo-EM Technique – Uncovered the Atomic Structure of a Key Alzheimer’s Protein for the First Time
Tau protein abnormal deposit is one of the most important characteristics for Alzheimer. Recently, a new finding published in Nature obtained high-resolution images of those protein deposit structures caused by Alzheimer and other neurodegenerative disease for the first time. These finding can help scientists understand how these protein harmful deposit process function at the molecular level, and help develop new treatments to prevent the formation of these proteins, and thus…