When pathogens invade the body, the innate immune system will play a role in resisting the invading pathogens. The innate immune system is the first line of defense. It can accurately detect viruses or bacteria, and then activate proteins to fight against pathogens. In order to better understand the working principle of the innate immune system in the body, researchers from research institutions such as the National Cancer Center Research…
TBK1
Cell: TBK1 Is the Blockage to Weight Loss
Highlights TBK1 operates at the intersection of energy expenditure and inflammation TBK1 deficiency attenuates HFD-induced obesity but exaggerates inflammation TBK1 represses energy expenditure by phosphorylating and inhibiting AMPK TBK1 attenuates NF-κB activation and mediates the anti-inflammatory effect of AMPK Do you ever wonder why fat body burns even fewer calories, or why dieting for weight loss always has bottlenecks? That’s because in both cases, our body tries to defend…