This study reveals how sleep deprivation affects microglia, and finds that TREM2 mediates sleep deprivation-induced microglia overactivation, and β-Amyloid protein (Aβ） deposition increases. Long-term chronic sleep deprivation regulates inflammation and the metabolic reaction of microglia and Aβ in the brain. With the accelerating pace of society and increasing work pressure, it is sometimes particularly luxurious for modern people to have a good sleep. However, a large number of studies…
Day: May 12, 2023
Molecular Mechanism of Melanoma Induced by CDK13 Mutant Protein
The RNA surveillance pathway can detect and interpret defective transcripts to ensure the fidelity of RNA. Recently, in a research report entitled “Oncogenic CDK13 mutations infinite nuclear RNA surveillance” published on the international journal Science, scientists from Howard Hughes Medical Research Institute and other institutions found a new mechanism that affects the occurrence of melanoma through research, which has a very broad and important significance for the treatment of multiple…