Creative Biomart Blog

Fri, 2016/06/17

New Fluorescent Method to Detect Nicotinamide Adenine Dinucleotide (NAD+)

Researchers have found a new method to detect NAD+, and they published their wonderful work on Science Magazine: http://science.sciencemag.org/content/352/6292/1474. Creative Biomart provides NAD+ related protein products for research applications. [table caption="Related Products" width="800" colwidth="100|200|180" colalign="left|left|center|center|center"] Cat. #,Product name,Source(Host),Species,Conjugate PARP1-4276R,Recombinant Rat PARP1 Protein,Mammalian Cells,Rat,His PARP2-12373M,Recombinant Mouse PARP2 Protein,Mammalian Cells,Mouse,His PARP4-156H,Recombinant Human PARP4 protein GST-ta

Thu, 2016/06/16

Perspective: Using microRNAs to Induce Single-cell variability

Newest article from Science Magazine: http://science.sciencemag.org/content/352/6292/1390 A single zygote with a defined DNA sequence gives rise to all the varied cells of the mammalian body. This variety of cell fates may arise in part from cell-to-cell variability in the gene expression programs of embryonic stem cells (ESCs). Three recent studies have taken different approaches to characterizing this variability in gene expression in stem cells. These results suggest that microRNAs (miRNAs) could play an important role in controlling and generating this variability. Pluripotent stem cells

Thu, 2016/05/26

Insight: the Mechanism to Maintain the Spindle at the Cell Center during Mitosis

Cell division is the most important and common events in life. However, the entire mechanism of cell division is still mysterious for us. Recently, scientists (Carlos Garzon-Coral, Horatiu A. Fantana, Jonathon Howard) found A force-generating machinery that can maintain the spindle at the cell center during mitosis, and they published their findings on Science Magazine (Science 27 May 2016: Vol. 352, Issue 6289, pp. 1124-1127 DOI: 10.1126/science.aad9745). Here, let us to appreciate their wonderful article. (Don’t forget that Creative Biomart can provide you molecular tools in cell division r

Thu, 2016/05/19

Global Standards for Stem-cell Research

Stem-cell research is one of the most popular research areas. More and more scientists pay their attention to this field. Now, new guidelines from the International Society for Stem Cell Research offer a model for self-regulation in contentious areas, write Jonathan Kimmelman and colleagues. What’s more, Creative Biomart provides you the best protein products for stem-cell research. Stem-cell research offers tremendous promise for biomedicine. It also raises vexing ethical and policy challenges. It can involve the destruction, creation and modification of human embryos, and has led to the pre

Thu, 2016/05/12

Tau Protein—Not Amyloid—May Be Key Driver of Alzheimer’s Symptoms

Tau proteins are the product of alternative splicing from a single gene, which in humans is designated MAPT (microtubule-associated protein tau) and is located on chromosome 17. They were discovered in 1975 in Marc Kirschner's laboratory at Princeton University. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become defective and n

Sat, 2016/05/07

Human Embryo Research Confronts Ethical ‘Rule’

Human embryo development is an important research area for the health of humans. However, there are many limits for Embryonic Development research applications. Here we share an article by Patrick Monahan about Human Embryo Research and Ethical ‘Rule’. This article can be obtained from http://science.sciencemag.org/ (Science 352 (6286), 640. [doi: 10.1126/science.352.6286.640]). The following is full text of this article: It’s easy to obey a rule when you don’t have the means to break it. For decades, many countries have permitted human embryos to be studied in the laboratory only up to 14 da

Mon, 2016/04/25

Precision Medicine: Researchers Push for Personalized Tumor Vaccines

Nowadays, precision medicine has become one of the hot topics in our daily life. Researchers want to treat some diseases according to the information of genes that the patient have in a more efficient way. Do you want to know the opinions of researchers about precision medicine? Here we share an article from nature.com (Nature/ doi:10.1038/nature.2016.19801). The full text is followed: It is precision medicine taken to the extreme: cancer-fighting vaccines that are custom designed for each patient according to the mutations in their individual tumors. With early clinical trials showing promis

Fri, 2016/04/15

JAK2 Inhibitors Target Aggressive Breast Cancers

Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. It is a member of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family (e.g. interferon receptors). Here we’d like to share a latest research about JAK2 gene in breast cancer. This article comes from www.sciencemag.org and www.ScienceTranslationalMedicine.org and you can get all detail from these sites. what's more, Creative Biomart can provide you product related to JAK2 of several sources, grades and formulations for research applications. INTRODUCTION Triple-n