Address: 45-16 Ramsey Road Shirley, NY 11967, USA    USA: 1-631-559-9269   Fax: 1-631-938-8127
UK: 44-207-048-3343  Email: info@creative-biomart.com

SERVICES

USA
45-16 Ramsey Road, Shirley, NY 11967, USA
TEL: 1-631-559-9269
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com
UK
St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK
TEL: 44-207-048-3343
facebook  twitter  linkedin  google plus
You Position:  Home >> Services >> Membrane Protein Services >> Custom Membrane Protein Production

Custom Membrane Protein Production

Creative Biomart is committed to providing advanced tools for protein expression and purification. As a leading supplier for reagents in the biotechnology field, we understand the importance of convenient and easy-to-use systems for high level expression and sample purification. We invite you to review our growing range of expression systems resulting from our experience in cloning, overexpression and purification.
Custom Membrane Protein Production
Creative Biomart offers services in the production and formulation of membrane and other proteins for various applications. The FoldEZTM platform was designed specifically to address issues associated with the discovery of therapeutics for low abundance membrane proteins, and primarily GPCRs and ion channels.

Creative Biomart's proprietary FoldEZTM technology utilizes an E. coli expression system designed to enhance expression and to direct the recombinant protein to cytosolic aggregates known as "inclusion bodies”. This enables a yield of up to 10,000 fold higher than seen with conventional recombinant membrane protein expression technologies. Yields using this method are typically between 5-50 mg per liter of cell culture medium. The aggregated recombinant protein is then taken through a series of proprietary purification and refolding steps to generate functional, native protein.

With FoldEZTM , multiple targets or multiple variants of a given membrane protein target can be produced quickly and in a parallel format. To date, more than 200 different GPCRs and ion channels have been cloned and expressed using FoldEZTM. The current rate of success in expression and refolding is more than 75% for any given new protein and has been steadily increasing in the past.

FoldEZTM is the basis of drug discovery technologies such as protein structure analysis and the generation of therapeutic antibodies directed against GPCRs.

Inquiry
We prefer payment by Check or Wire transfer. Payment by Credit Card (Visa/ MasterCard only) is also acceptable . In order to facilitate our processing with the credit card charge, please provide the following information by fax or over phone:

  • Card number
    Expiration (month/year)
    Card type (VISA/ Mastercard only)
    Name on the card
    Amount to be paid
    Security code
    Billing Address
    Card holder Tel number

    You can order by phone, fax, or email.
    Email: info@creative-biomart.com (preferable)
    Phone: 1-631-559-9269
    Fax: 1-631-938-8127
  • * E-mail Address:
    Name:
    Phone:
    * Service & Products Interested:
    Project Description:
    * Verification code: biomart   
    Please review Creative Biomart's privacy policy for more information.
    Submit
  • 45-16 Ramsey Road, Shirley, NY 11967, USA
    TEL: 1-631-559-9269
    FAX: 1-631-938-8127
    EMAIL:
    info@creative-biomart.com

    St John's Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK
    TEL: 44-207-048-3343

    facebook twitter linkedin google plus google plus

  • Join 10 other subscribers