The GenePowerTM Controlled Randomization technology allows you to accurately direct the effective frequency of random nucleotide substitutions. And unlike error-prone PCR, you decide exactly which part(s) of the gene are affected—randomize the entire open reading frame or confine the mutagenesis to specific regions.
With chemical based mutagenesis, we provide you with a convenient and cheap mutagenesis method for the generation of low mutation frequency libraries.
With our mutator strain library, we provide you with an approximately higher mutation rate strategy with the specific DNA.
Site-Saturation Mutagenesis Service at Creative BioMart systematically replaces WT amino acid coding sequences with all 19 non-wild type amino acids at the position(s) you specify. Well-known as sequential permutation, site-saturation mutagenesis in combination with a powerful screening assay is the most systematic mutation strategy to identify amino acid substitutions that fulfill your protein engineering goals.