Recombinant Human COL3A1 protein
Cat.No. : | COL3A1-19587H |
Product Overview : | Recombinant Human COL3A1 protein was expressed in Pichia pastoris. Six times ploygene of a human-like collagen monomeric gene(EF376007), which is designed and synthesized according to human type III collagen, the unique character of collagenous domain, especially, which is made up of total repeat of "Gly-x-y" unit, and aimed at improving the water-solubility. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
Source : | Pichia Pastoris |
Species : | Human |
Form : | Lyophilized from water, No additives. |
Molecular Mass : | The RHC-99S has a predicted molecular mass of 55.0kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of 112kDa due to Linear protein. |
Purity : | >99.5% by HPLC |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Use sterile water to dissolve and dilute to the required concentration. Should be used as soon as possible after dissolution. |
Gene Name : | COL3A1 collagen, type III, alpha 1 [ Homo sapiens ] |
Official Symbol : | COL3A1 |
Synonyms : | COL3A1; collagen, type III, alpha 1; EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant; collagen alpha-1(III) chain; collagen, fetal; alpha1 (III) collagen; Ehlers-Danlos syndrome type IV, autosomal dominant; EDS4A; FLJ34534; |
Gene ID : | 1281 |
mRNA Refseq : | NM_000090 |
Protein Refseq : | NP_000081 |
MIM : | 120180 |
UniProt ID : | P02461 |
Chromosome Location : | 2q32.2 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Endothelins, organism-specific biosystem; |
Function : | SMAD binding; extracellular matrix structural constituent; integrin binding; integrin binding; platelet-derived growth factor binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Col3a1-1281M | Recombinant Mouse Col3a1 Protein, His-tagged | +Inquiry |
Col3a1-1280R | Recombinant Rat Col3a1 Protein, His-tagged | +Inquiry |
COL3A1-3440H | Recombinant Human COL3A1 Protein, His-tagged | +Inquiry |
COL3A1-1650H | Recombinant Human COL3A1 Protein, GST-tagged | +Inquiry |
COL3A1-1179R | Recombinant Rat COL3A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
COL3A1-18B | Native Bovine COL3A1 Protein | +Inquiry |
COL3A1-001H | Native Human COL3A1 Protein | +Inquiry |
COL3A1-17B | Native Bovine COL3A1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionUnderstanding the specific genetic and protein alterations in vEDS patients can help tailor individualized treatment strategies based on the patient's unique molecular profile.
Yes, analysis of COL3A1 protein levels in prenatal samples may provide valuable information for assessing the risk of vEDS in the developing fetus.
Elevated or decreased levels of COL3A1 protein may serve as potential biomarkers for early detection and risk assessment of vEDS, especially in at-risk individuals or families.
Challenges include the need for standardized assays and reference ranges for COL3A1 protein levels, as well as the interpretation of results in the context of individual patient variability.
Yes, monitoring changes in COL3A1 protein levels may provide insights into disease progression and response to treatment in vEDS patients.
Customer Reviews (3)
Write a reviewThis protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.
The COL3A1 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.
the COL3A1 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.
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