Recombinant Human PPM1B, fused with N-His tag, was expressed in E. coli.
Protein phosphatase 1B is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death.
20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
54.6kDa(including fusion tag)
494aa(including fusion tag)
WB, ELISA, IP, antibody production, protein array
Store at -80centigrade and avoid repeated freeze-thaw cycles.