Recombinant Human PRMT5/MEP50 complex Protein, Flag/His-tagged
Cat.No. : | PRMT5-178H |
Product Overview : | Human recombinant PRMT5 in complex with human recombinant MEP50, produced by co-expression in an insect cell/baculovirus expression system with N-terminal Flag (PRMT5), N-terminal His (MEP50). |
- Specification
- Gene Information
- Related Products
Source : | Insect cell |
Species : | Human |
Tag : | Flag/His |
Form : | 50 mM Tris/HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM TCEP, 20% (v/v) glycerol. |
Molecular Mass : | 73.7/39.90 kDa |
Protein length : | PRMT5 2-637(C-term.), MEP50 2-342 (C-term.) |
Purity : | >95% by SDS-PAGE |
Storage : | Store at -80centigrade. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles. |
Gene Name : | PRMT5 protein arginine methyltransferase 5 [ Homo sapiens ] |
Official Symbol : | PRMT5 |
Synonyms : | PRMT5; protein arginine methyltransferase 5; HRMT1L5, SKB1, skb1 (S. pombe) homolog , SKB1 homolog (S. pombe); protein arginine N-methyltransferase 5; SKB1Hs; SKB1 homolog; jak-binding protein 1; 72 kDa ICln-binding protein; HMT1 hnRNP methyltransferase |
Gene ID : | 10419 |
mRNA Refseq : | NM_001039619 |
Protein Refseq : | NP_001034708 |
MIM : | 604045 |
UniProt ID : | O14744 |
Chromosome Location : | 14q11.2 |
Pathway : | E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Signali |
Function : | histone-arginine N-methyltransferase activity; methyltransferase activity; protein binding; protein-arginine omega-N symmetric methyltransferase activity; ribonucleoprotein complex binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
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PRMT5-1771H | Recombinant Human PRMT5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Prmt5-5133M | Recombinant Mouse Prmt5 Protein, Myc/DDK-tagged | +Inquiry |
PRMT5-3004H | Recombinant Human PRMT5 Protein, MYC/DDK-tagged | +Inquiry |
PRMT5-7125M | Recombinant Mouse PRMT5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRMT5-2577HCL | Recombinant Human PRMT5 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1859 | PRMT5 Homogeneous Assay Kit | +Inquiry |
Kit-1858 | PRMT5 Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, there are ongoing clinical trials investigating the efficacy of PRMT5 inhibitors in various cancer types.
PRMT5 influences cellular differentiation by regulating the expression of genes involved in the process.
Yes, there is interest in exploring combination therapies involving PRMT5 inhibitors with other anticancer agents to enhance treatment efficacy.
PRMT5 methylates histone proteins, leading to changes in chromatin structure and gene expression, thus playing a crucial role in epigenetic regulation.
PRMT5 has been implicated in neurodegenerative diseases, and understanding its role may provide insights into developing therapies for conditions like Alzheimer's and Parkinson's disease.
Customer Reviews (3)
Write a reviewGreat performance in ELISA.
Its purity and functionality ensure precise and reproducible results, enabling me to achieve my research objectives with confidence.
The PRMT5 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.
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