Recombinant Human SRD5A2 protein
Cat.No. : | SRD5A2-81H |
Product Overview : | Recombinant Human SRD5A2 was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). |
Source : | Wheat Germ |
Species : | Human |
Form : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Molecular Mass : | 28 Kd |
AA Sequence : | MQVQCQQSPVLAGSATLVALGALAL YVAKPSGYGKHTESLKPAATRLPAR AAWFLQELPSFAVPAGILARQPLSL FGPPGTVLLGLFCLHYFHRTFVYSL LNRGRPYPAILILRGTAFCTGNGVL QGYYLIYCAEYPDGWYTDIRFSLGV FLFILGMGINIHSDYILRQLRKPGE ISYRIPQGGLFTYVSGANFLGEIIE WIGYALATWSLPALAFAFFSLCFLG LRAFHHHRFYLKMFEDYPKSRKALI PFIF |
Applications : | Antibody Production; Functional Study: Recommended usage only, not validated yet. Compound Screening: Recommended usage only, not validated yet. |
Notes : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) [ Homo sapiens ] |
Official Symbol : | SRD5A2 |
Synonyms : | SRD5A2; steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2); 3-oxo-5-alpha-steroid 4-dehydrogenase 2; S5AR 2; SR type 2; 5 alpha-SR2; type II 5-alpha reductase; steroid 5-alpha-reductase 2; 3-oxo-5 alpha-steroid 4-dehydrogenase 2; MGC138457; |
Gene ID : | 6716 |
mRNA Refseq : | NM_000348 |
Protein Refseq : | NP_000339 |
UniProt ID : | P31213 |
Chromosome Location : | 2p23.1 |
Pathway : | Androgen biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem; Steroid hormone biosynthesis, organism-specific biosystem; |
Function : | 3-oxo-5-alpha-steroid 4-dehydrogenase activity; sterol 5-alpha reductase activity; |
Products Types
◆ Recombinant Protein | ||
SRD5A2-5394R | Recombinant Rat SRD5A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRD5A2-8707M | Recombinant Mouse SRD5A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRD5A2-4144H | Recombinant Human SRD5A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRD5A2-717C | Recombinant Cynomolgus Monkey SRD5A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRD5A2-2100H | Recombinant Human SRD5A2 Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
SRD5A2-1480HCL | Recombinant Human SRD5A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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