Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email:
Inquiry now !
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification code:
Please input "biomart" as verification code.

Your Position:  Home >> Services >> Site-Directed Mutagenesis

Site-Directed Mutagenesis

The GenePowerTM site-directed mutagenesis service introduces single or multiple mutations (substitutions, insertions, deletions, or truncations) into existing DNA sequences quickly and economically.

We can replace any protein residue with the residue you specify. A stretch of up to 7 neighboring amino acids can be replaced simultaneously and considered one mutation. Mutations can be introduced in more than one location.

• Investigate active sites, structure-function relationships, nucleic acid–protein interactions, etc.
• Test functional elements (promoter regions, terminator sequences, etc.).
• Construct fusion proteins and tagged proteins.
• Design knockout constructs.
• Generate alternative splice forms.
• Conduct alanine scans to identify protein functional domains.
• Economical alternative to synthetic gene construction for constructs smaller than ~1 kb.
• Mutations exactly where you need them, without the risk of introducing unwanted mutations.
• Unlike "quick change" strategies, the vector is not subjected to PCR—just the insert.
• Insert size can be as large as 6–8 kb.
• No mutations in the vector backbone.
• Mutations can be clustered or far apart, with the same cost and production time.
• Fast turnaround times.
• Template constructs are stored for at least 2 years at no charge and longer-term storage is available.
• Full sequence verification of insert DNA.

Welcome to contact us or send an email to for project quotations and more detailed information.
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

facebook twitter linkedin google plus google plus

Join 10 other subscribers

Easy access to products and services you need from our library via powerful searching tools
Copyright © 2007 - 2017 Creative Biomart. All Rights Reserved.