ADHP [10-Acetyl-3,7-dihydroxyphenoxazine]

• Cat.No.: DYE-164

Specification

• Description: 10-Acetyl-3,7-dihydroxyphenoxazine (ADHP) is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2.This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength of 585-595 nm. In a 96-well plate format, ADHP enables detection of H2O2 at a concentration as low as 5 pmol per 100 μl sample.
• CAS number: 119171-73-2
• Molecular Mass: 257.24
• Formula: C14H11NO4
• Ex(nm): 571
• Em(nm): 585
• Solvent: DMSO
• Storage: Store at -20°C in the dark. Dessicated.

Reviews

03/14/2018

Provides reliable and consistent results in protein quantification in clinical samples.

02/07/2016

Shows exceptional binding affinity to small molecules in drug target screening assays.

Q&As

Can ADHP be pharmacologically targeted or manipulated, and what are the potential therapeutic applications?

ADHP represents a potential target for pharmacological intervention, offering opportunities for therapeutic applications in relevant conditions or diseases.

What are the interacting partners or binding partners of ADHP, and what is the functional significance of these interactions?

ADHP interacts with specific partners or molecules, and these interactions are essential for its functional regulation or involvement in complex cellular processes.

Can ADHP be regulated by specific signaling pathways or cellular stimuli, and what are the downstream effects of its activation or inhibition?

ADHP can be regulated by specific signaling pathways or cellular stimuli, leading to downstream effects on cellular processes or functional outcomes.

What is the expression pattern of ADHP across different tissues or cell types, and are there any tissue-specific or developmental regulations?

ADHP shows an expression pattern across different tissues or cell types, and its tissue-specific or developmental regulations provide insights into its physiological roles.

Does ADHP play a role in specific cellular processes or biological pathways, and if so, what are the underlying mechanisms?

ADHP plays a role in specific cellular processes or biological pathways, and the underlying mechanisms elucidate its functional contributions.

What is the functional consequence of ADHP deficiency or overexpression, and does it lead to any cellular or physiological phenotypes?

Deficiency or overexpression of ADHP can result in cellular or physiological phenotypes, highlighting its essential role and the consequences of dysregulation.

What is the cellular localization of ADHP, and does it exhibit any subcellular compartmentalization or dynamic translocation?

ADHP exhibits a specific cellular localization, and its potential subcellular compartmentalization or dynamic translocation suggests distinct roles in different cellular contexts.

Can ADHP modulate gene expression or transcriptional activity, and what are the target genes or regulatory elements involved?

ADHP has the potential to modulate gene expression or transcriptional activity, involving specific target genes or regulatory elements.

What is the evolutionary conservation of ADHP across different species, and does it have conserved functions or divergent roles?

The evolutionary conservation of ADHP across different species suggests conserved functions or divergent roles in specific organisms, providing insights into its evolutionary significance.

Is there any evidence of post-translational modifications on ADHP, and how do they influence its stability, activity, or intracellular localization?

Post-translational modifications on ADHP have been observed, and they have implications for its stability, activity, or intracellular localization.