Recombinant Human Defensin, Beta 4A

• Cat.No.: DEFB4A -5387H
• Product Overview: Recombinant HumanDefensin beta 4 is a single, non-glycosylated polypeptide chain containing 50amino acids.

Specification

• Cat. No.: DEFB4A -5387H
• Description: DEFB4A also known as skin-antimicrobial peptide 1(SAP1) is a peptide that in humans is encoded by the DEFB4 (defensin, beta 4)gene. Human DEFB4A is a cysteine-rich cationic low molecularweight antimicrobial peptide recently discovered in lesional skin.
• Source: E. coli
• Species: Human
• Form: Lyophilized from asterile filtered solution in 20 mM PBS, pH 7.4 + 130 mM NaCl.
• Molecular Weight: 6.0 kDa
• Purity: > 98% by HPLC andSDS-PAGE.
• Endotoxin Level: < 0.1 ng/µg ofDefensin beta 4.
• Biological Activity: Determined by itsability to chemoattract human monocytes using a concentration range of 0.1-50ng/mL.
• Sequence: EFELDRICGYGTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
• Reconstitution: Centrifuge vialprior to opening. Add sterile distilled water or aqueous buffer to a concentrationof 0.1-1.0 mg/mL. Further dilutions should be made in appropriate bufferedsolutions.
• Storage: Stable at 2-8°C, butbest kept desiccated -20°C. Upon reconstitution, stable for up to 1 week at2-8°C. For longer term, store in working aliquots below -20°C. Avoid repeatedfreeze/thaw cycles.
• OfficialSymbol: DEFB4A

Gene Information

• Gene Name: DEFB4A defensin, beta 4A [ Homosapiens ]
• Synonyms: DEFB4A; defensin,beta 4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102; hBD-2;beta-defensin 4A; Skin-antimicrobial peptide 1; defensin, beta 2; defensin,beta 4; OTTHUMP00000159651; skin-antimicrobial peptide 1; Defensin, beta 2;Skin-antimicrobial peptide 1
• Gene ID: 1673
• mRNA Refseq: NM_004942
• Protein Refseq: NP_004933
• MIM: 602215
• UniProt ID: O15263
• Chromosome Location: 8p23.1