Active Recombinant Mouse Insulin-Like Growth Factor Binding Protein 1
Cat.No. : | Igfbp1-5643M |
Product Overview : | RecombinantMouse Igfbp1 protein was expressed in Murine myeloma cellline. Ala26-Asn272. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Igfbp1-5643M |
Description : | Theinsulin-like growth factor binding protein (IGFBP) family consists of six structurallyrelated proteins that bind IGF with high affinity. These proteins share conservedcysteine-rich N- and C-terminal regions that participate in IGF binding.IGFBPs regulate the bioavailability of IGFs and modulate their biologicalactivities, both positively and negatively. Some IGFBPs also have intrinsicbioactivity that is IGF-independent. Post-transitional modifications of theIGFBPs, including glycosylation, phosphorylation and proteolysis, influenceIGF binding affinities and tissue localization, affecting both theIGF-dependent and independent functions. |
Source : | Mammalian cells |
Form : | Suppliedas a 0.2 um filtered solution in Acetonitrile and TFA. |
N-terminalSequence : | Ala26 |
MolecularWeight : | 27 kDa |
Activity : | Measuredby its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7human breast adenocarcinoma cells. The ED50 for this effect is typically 3-15μg/mL in the presence of 5 ng/mL rmIGF-I. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 34 kDa,reducing conditions. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 1month, 2 to 8 °C under sterile conditions after opening. |
Gene Name : | Igfbp1 insulin-like growthfactor binding protein 1 [ Mus musculus ] |
Official Symbol : | Igfbp1 |
Synonyms : | Igfbp1; insulin-likegrowth factor binding protein 1; insulin-like growth factor-bindingprotein 1; IBP-1; IGF-binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDINGPROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); IGFBP-1; Igfbp-1 |
Gene ID : | 16006 |
mRNA Refseq : | NM_008341 |
Protein Refseq : | NP_032367 |
UniProt ID : | P47876 |
Chromosome Location : | 11 |
Pathway : | Diabetes pathways;Disease; Myometrial Relaxation and Contraction Pathways; Regulation ofInsulin-like Growth Factor (IGF) Activity by Insulin-like Growth FactorBinding Proteins (IGFBPs) |
Function : | growth factorbinding; insulin-like growth factor binding |
Products Types
◆ Recombinant Protein | ||
IGFBP1-574M | Recombinant Mouse IGFBP1 Protein (26-272 aa), His-SUMO-tagged | +Inquiry |
IGFBP1-79H | Active Recombinant Human IGFBP1 Protein | +Inquiry |
Igfbp1-988R | Recombinant Rat Igfbp1 Protein, His-tagged | +Inquiry |
Igfbp1-10568M | Recombinant Mouse Igfbp1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP1-2663R | Recombinant Rat IGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
IGFBP1-612H | Native Human Insulin-like Growth Factor Binding Protein 1 | +Inquiry |
◆ Lysates | ||
IGFBP1-1482CCL | Recombinant Cynomolgus IGFBP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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