Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Rabbit Anti-Human Bone Marrow Stromal Cell Antigen 1 Monoclonal Antibody

Rabbit Anti-Human Bone Marrow Stromal Cell Antigen 1 Monoclonal Antibody

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Chicken(1)
Human(7)
Mouse(6)
Rat(9)
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Fc(1)
GST(1)
His(5)
Cat.No.:
CAB11482RH
Product Overview:
Rabbit monoclonal antibody to Human bone marrow stromal cell antigen 1.
Antigen Description:
Human CD157, also known as bone marrow sromal cell antigen 1(BST-1), is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. As a 45-kDa surface glycoprotein with a GPI anchor, the CD157 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule and the second features adhesion/signalling properties. CD157 shares several characteristics with CD38, including a similar amino acid sequence and enzymic functions. Both molecules are involved in the metabolism of NAD+, and the CD157 gene is synthenic on 4p15 with CD38, with which it also shares a unique genomic organization. Their conservation in phylogeny is striking evidence for their relevance in the life and death cycle of the cell.
Specificity:
Human CD157 / BST1. No cross-reactivity in ELISA with Mouse BST1, Human cell lysate (293 cell line).
Immunogen:
Recombinant Human CD157 / BST1 Protein
Host:
Rabbit
Isotype:
Rabbit IgG
Species:
Human
Clone:
030
Applications:
Western Blot; ELISA
Dilution:
Western blot: This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect Human BST1 in WB. Using a DAB detection system, the detection limit for Human BST1 is approximately 0.5 ng/lane under non-reducing condition. Use of this antibody under reducing conditions is not recommended.Direct ELISA: This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect Human BST1. The detection limit for Human BST1 is approximately 0.0049 ng/well.
Preparation:
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Human CD157 / BST1.
Format:
0.2 μm filtered solution in PBS with 5% trehalose
Storage:
This antibody can be stored at 2-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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