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Native Human CTSG protein

Cat.No.: CTSG-1649H
Product Overview: Native Human CTSG was purified from Human Neutrophil.
Description: This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
Source: Human Neutrophil
Species: Human
Form: Salt-free lyophilized solid.
Bio-activity: 2-4 units per mg protein
Molecular Mass: 23500
Purity: >=95% by SDS-PAGE
Unit Definition: One unit is defined as the amount of enzyme that hydrolyzes one umole of Suc-Ala-Ala Pro-Phe-pNA (1 mM) per minute at 25 centigrade in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
Storage: Stored at -20 centigrade
Gene Name: CTSG cathepsin G [ Homo sapiens ]
Official Symbol: CTSG
Synonyms: CTSG; cathepsin G; CG; CATG; MGC23078;
Gene ID: 1511
mRNA Refseq: NM_001911
Protein Refseq: NP_001902
MIM: 116830
UniProt ID: P08311
Chromosome Location: 14q12
Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Activation of Matrix Metalloproteinases, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
Function: heparin binding; peptidase activity; serine-type endopeptidase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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