Active Recombinant Human PREP, His-tagged
Cat.No. : | PREP-2377H |
Product Overview : | Recombinant Human PREP (Leu2-Pro710) fused with an N-terminal Met and 6-His tag, was expressed in Sf 21 Cells |
- Specification
- Gene Information
- Related Products
Cat. No. : | PREP-2377H |
Description : | The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. |
Source : | Sf 21 (baculovirus) |
Molecular Mass : | 81 kDa |
Predicted N terminal : | Met |
Formulation : | Supplied as a 0.2 µm filtered solution in MES, NaCl and Glycerol. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Activity : | Measured by its ability to convert the substrate benzyloxycarbonyl-Gly-Pro-7-amido-4-methylcoumarin (Z-GP-AMC) to Z-Gly-Pro and 7-amino-4-methylcoumarin (AMC). The specific activity is >3,500 pmol/min/µg, as measured under the described conditions. |
EndotoxinLevel : | <1.0 EU per 1 μg of the protein by the LAL method. |
Storage : | 6 months from date of receipt, 20 to 70 °C as supplied. Avoid repeated freezethaw cycles. |
OfficialSymbol : | PREP |
Gene Name : | PREP prolyl endopeptidase [ Homo sapiens ] |
Synonyms : | prolyl endopeptidase; PE; PEP; MGC16060; PREP; prolyl oligopeptidase; post-proline cleaving enzyme; dJ355L5.1 (prolyl endopeptidase); Post-proline cleaving enzyme; EC 3.4.21.26 |
Gene ID : | 5550 |
mRNA Refseq : | NM_002726 |
Protein Refseq : | NP_002717 |
MIM : | 600400 |
UniProt ID : | P48147 |
Chromosome Location : | 6q22 |
Function : | serine-type endopeptidase activity; serine-type peptidase activity; peptide binding |
Products Types
◆ Recombinant Protein | ||
PREP-3415R | Recombinant Rhesus Macaque PREP Protein, His (Fc)-Avi-tagged | +Inquiry |
PREP-4324R | Recombinant Rat PREP Protein, His (Fc)-Avi-tagged | +Inquiry |
PREP-0001H | Recombinant Human PREP Protein | +Inquiry |
Prep-5107M | Recombinant Mouse Prep Protein, Myc/DDK-tagged | +Inquiry |
PREP-2376H | Active Recombinant Human PREP Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PREP-001MCL | Recombinant Mouse PREP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe protein may be involved in cardiovascular disease, but the specific mechanism is not fully understood, and further research is needed to validate it.
PREP protein has been implicated in several diseases, including neurological disorders such as Alzheimer's disease, stroke, and Parkinson's disease.
Some studies suggest that PREP protein may be involved in the development of neurodegenerative diseases, but the specific mechanism and effects need to be further studied.
Studies have shown that PREP protein is abnormally expressed in some tumors, which may be related to the development and progression of tumors, but the specific role still needs to be further studied.
The role of PREP protein in digestive diseases is currently limited, and more research is needed to further explore its role and potential applications.
PREP protein can participate in the regulation of protein folding and aggregation, so it may have potential in the prevention of protein aggregation diseases.
Customer Reviews (3)
Write a reviewThe safety is very high, so you can use it with confidence.
PREP activity is maintained for a very long time and can be maintained for a long time.
It is very resistant to pollution and is not easily polluted.
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