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Active Recombinant Human TIMP3 protein, Fc-tagged

Cat.No. : TIMP3-002H
Product Overview : Recombinant Human TIMP3(Cys24-Pro211) fused with Fc region of human IgG1 at N-terminal was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to induce alkaline phosphatase production.
Molecular Mass : The predicted molecular mass is 48 kDa, and the apparent molecular mass is approximately 55 kDa in SDS-PAGE under reducing conditions.
Protein length : Cys24-Pro211
Endotoxin : <0.06 EU/μg as determined by LAL test.
Purity : >95%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade. Avoid freeze/thaw cycles.
Reconstitution : Reconstitute with sterile water to a concentration of 1mg/ml. Add 1xPBS to the desired protein concentration.
Gene Name : TIMP3 TIMP metallopeptidase inhibitor 3 [ Homo sapiens ]
Official Symbol : TIMP3
Synonyms : TIMP3; TIMP metallopeptidase inhibitor 3; SFD, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); metalloproteinase inhibitor 3; TIMP-3; MIG-5 protein; protein MIG-5; tissue inhibitor of metalloproteinases 3; SFD; K222; K222TA2; HSMRK222;
Gene ID : 7078
mRNA Refseq : NM_000362
Protein Refseq : NP_000353
MIM : 188826
UniProt ID : P35625
Chromosome Location : 22q12.3
Pathway : Endochondral Ossification, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
Function : enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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09/05/2019

    Manufacturers might offer customization options, such as different variants or modifications of the TIMP3 protein, to cater to specific research requirements.

    01/28/2018

      Such support helps researchers overcome challenges and obtain reliable results.

      06/06/2016

        This flexibility allows researchers to focus on specific aspects of TIMP3 protein functionality, regulation, or disease associations, enhancing the relevance and applicability of their work.

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