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Active Recombinant Mouse EGF, MIgG2a Fc-tagged

Cat.No. : EGF-316M
Product Overview : The extracellular domain of mouse EGF (AAH17681.1) (Asn960-Arg1012) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell
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  • Gene Information
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Description : This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as alarge precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factorpeptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferationand differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor,epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation ofthis gene has been associated with the growth and progression of certain cancers. Alternate splicing results inmultiple transcript variants
Source : CHO cellS
Species : Mouse
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in a cell proliferation assay.
Molecular Mass : 32KDa (monomer)
AA Sequence : Asn960-Arg1012
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Egf epidermal growth factor [ Mus musculus ]
Official Symbol : EGF
Synonyms : EGF; epidermal growth factor; pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); AI790464;
Gene ID : 13645
mRNA Refseq : NM_010113
Protein Refseq : NP_034243
Pathway : Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem;
Function : calcium ion binding; epidermal growth factor receptor binding; epidermal growth factor receptor binding; growth factor activity; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is EGF protein produced in the body? 02/07/2022

The body naturally produces EGF protein, and it can also be synthesized for clinical applications using biotechnological methods.

Are there any side effects associated with the clinical use of EGF protein? 12/06/2021

Generally, EGF is well-tolerated, but localized irritation or redness at the application site can occur in some cases.

Can EGF be used in the treatment of burns? 11/03/2021

Yes, EGF has been explored for its potential in treating burns by promoting the regeneration of damaged skin tissue.

What are the primary clinical applications of EGF protein? 10/19/2021

EGF protein is widely used in clinical settings for wound healing, tissue regeneration, and certain dermatological conditions.

Is EGF used in cosmetic products, and if so, for what purpose? 09/28/2019

Yes, EGF is a common ingredient in some cosmetic products due to its ability to promote skin rejuvenation and reduce the appearance of fine lines and wrinkles.

Customer Reviews (3)

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Reviews
01/27/2020

    This can be advantageous in understanding disease mechanisms and developing novel therapeutics.

    04/12/2018

      The manufacturer can provide detailed documentation on the quality control measures undertaken during protein production and purification.

      05/09/2016

        The manufacturer can offer technical expertise and guidance to researchers regarding the proper use, handling, and storage of EGF protein.

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