Active Recombinant Mouse EGF, MIgG2a Fc-tagged
Cat.No. : | EGF-316M |
Product Overview : | The extracellular domain of mouse EGF (AAH17681.1) (Asn960-Arg1012) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as alarge precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factorpeptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferationand differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor,epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation ofthis gene has been associated with the growth and progression of certain cancers. Alternate splicing results inmultiple transcript variants |
Source : | CHO cellS |
Species : | Mouse |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured in a cell proliferation assay. |
Molecular Mass : | 32KDa (monomer) |
AA Sequence : | Asn960-Arg1012 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | Egf epidermal growth factor [ Mus musculus ] |
Official Symbol : | EGF |
Synonyms : | EGF; epidermal growth factor; pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); AI790464; |
Gene ID : | 13645 |
mRNA Refseq : | NM_010113 |
Protein Refseq : | NP_034243 |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem; |
Function : | calcium ion binding; epidermal growth factor receptor binding; epidermal growth factor receptor binding; growth factor activity; protein binding; |
Products Types
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◆ Native Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
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Q&As (5)
Ask a questionThe body naturally produces EGF protein, and it can also be synthesized for clinical applications using biotechnological methods.
Generally, EGF is well-tolerated, but localized irritation or redness at the application site can occur in some cases.
Yes, EGF has been explored for its potential in treating burns by promoting the regeneration of damaged skin tissue.
EGF protein is widely used in clinical settings for wound healing, tissue regeneration, and certain dermatological conditions.
Yes, EGF is a common ingredient in some cosmetic products due to its ability to promote skin rejuvenation and reduce the appearance of fine lines and wrinkles.
Customer Reviews (3)
Write a reviewThis can be advantageous in understanding disease mechanisms and developing novel therapeutics.
The manufacturer can provide detailed documentation on the quality control measures undertaken during protein production and purification.
The manufacturer can offer technical expertise and guidance to researchers regarding the proper use, handling, and storage of EGF protein.
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