Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-097-1828   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Human CD40, MIgG2a Fc-tagged

Recombinant Human CD40, MIgG2a Fc-tagged

   Share
"CD40" Related Products.
By Species
+Expand -Collapse
By Source
+Expand -Collapse
By Tag
Fc(11)
Fc-His(3)
Hi & Fc & Avi(1)
His(17)
His & Avi(1)
His/Fc(1)
Human(6)
N/A(3)
+Expand -Collapse
Cat.No.:
CD40-105H
Product Overview:
The extracellular domain of human CD40 (AAH12419.1)(Glu21-Arg193) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell
Description:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Source:
CHO cells
Species:
Human
Tag:
MIgG2a Fc-tagged
Form:
Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity:
Measured by its binding ability in a functional ELISA.
Molecular Mass:
45KDa (monomer)
AA Sequence:
Glu21-Arg193
Endotoxin:
<0.06 eu/μg as determined by lal test.>
Purity:
>98%, by SDS-PAGE under reducing conditions.
Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution:
Reconstitute at 100μg/ml in sterile PBS.
Warning:
Avoid freeze/thaw cycles.


Online Inquiry    
Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
Please input "biomart" as verification code.
Please review Creative Biomart's privacy policy for more information.
Price does not include shipping and packaging costs.Request quote for final price.

If you have any other questions, please call
+1-631-559-9269.

online inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-097-1828
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

facebook twitter linkedin google plus google plus

Join 10 other subscribers

24x7
CUSTOMER SERVICE
Easy access to products and services you need from our library via powerful searching tools
Copyright © 2007 - 2017 Creative Biomart. All Rights Reserved.