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Recombinant Human Slit Homolog 2 (Drosophila)

Cat.No. : SLIT2-965H
Product Overview : Recombinant human Slit2-N produced in293 cellsis a 1088 amino acid glycoprotein corresponding to the N-terminal portion of the full length Slit2 precursor. Due to glycosylation Slit2-N migrates at an apparent molecular weight of approximately 110.0-116.0 kDa by SDS-PAGE analysis under reducing conditions.
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  • Gene Information
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Cat. No. : SLIT2 -965H
Description : Slit2 is a member of the Slit family that signals through the Roundabout (Robo) receptor as a repellent for axon guidance and neuronal migration, and can also act as a chemoattractant to vascular endothelial cells and a chemotaxis inhibitor for leukocytes. Slit2 is expressed primarily in the fetal lung, kidney, and adult spinal cord, and to a lesser extent in adult adrenal gland, thyroid and trachea. Slit2 is initially synthesized as a 1499 amino acid precursor, which is subsequently cleaved into N-terminal and C-terminal fragments, designated as Slit2-N and Slit2-C respectively. The neurodevelopment related activities, as measured by the ability to repel olfactory bulb axons and to induce branching in dorsal root ganglia axons, are contained only in the N-terminal fragment.
Source : 293 cells.
Purity : 98 % (SDS-PAGE, HPLC).
Endotoxin Level : < 0.1 ng per ug of Slit2-N.
Stabilizer : None.
Formulation : Lyophilized.
Biological Activity : Data not available!
Stability : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human Slit2-N should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.
Gene Name : SLIT2 slit homolog 2 (Drosophila) [ Homo sapiens ]
Synonyms : SLIT2;slit homolog 2 (Drosophila); SLIL3; Slit-2; FLJ14420; slit (Drosophila) homolog 2; Slit homolog 2 protein; Slit homolog 2 protein N-product; Slit homolog 2 protein C-product; FLJ14420; slit homolog 2
Gene ID : 9353
mRNA Refseq : NM_004787
Protein Refseq : NP_004778
MIM : 603746
UniProt ID : O94813
Chromosome Location : 4p15.2
Pathway : Axon guidance
Function : calcium ion binding; receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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