Recombinant Human Heat Shock 22kDa Protein 8
Cat.No. : | HSPB8-1254H |
Product Overview : | Recombinant Human Heat Shock Protein 22 was expressed inE.Coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HSPB8-1254H |
Description : | HSP22 displays temperature-dependent chaperone activity. HSP-22 acts as a mn(2+)-dependent serine-threonine- specific protein kinase. we are not convinced that this is its true role. Defects in HSPB8 are a cause of distal hereditary motor neuropathy type ii (DHMN2) also known as distal spinal muscular atrophy (DSMA) and spinal muscular atrophy of the charcot-marie-tooth type. it is an autosomal dominant disorder of lower motor neurons characterized by distal muscle weakness. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Formulation : | The HSP22 protein was lyophilized from a concentrated (1mg/ml) solution containing 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 15mMβ-ME. |
Solubility : | It is recommended to reconstitute the lyophilized HSP22 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Stability : | Lyophilized HSP22 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSP22 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Immunological Activity : | Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSP22. |
Gene Name : | HSPB8 heat shock 22kDa protein 8 [ Homo sapiens ] |
Synonyms : | heat shock 22kDa protein 8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; HSPB8; E2-induced gene 1; protein kinase H11; heat shock protein beta-8; heat shock 27kDa protein 8; small stress protein-like protein HSP22; HspB8; CRYAC; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22 |
Gene ID : | 26353 |
mRNA Refseq : | NM_014365 |
Protein Refseq : | NP_055180 |
MIM : | 608014 |
UniProt ID : | Q9UJY1 |
Chromosome Location : | 12q24.23 |
Function : | protein serine/threonine kinase activity; identical protein binding |
Products Types
◆ Recombinant Protein | ||
HSPB8-1123H | Recombinant Human HSPB8 Protein, His (Fc)-Avi-tagged | +Inquiry |
Hspb8-3457M | Recombinant Mouse Hspb8 Protein, Myc/DDK-tagged | +Inquiry |
HSPB8-2609R | Recombinant Rat HSPB8 Protein, His (Fc)-Avi-tagged | +Inquiry |
HSPB8-045H | Recombinant Human HSPB8 Protein | +Inquiry |
HSPB8-1991R | Recombinant Rhesus Macaque HSPB8 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HSPB8-5345HCL | Recombinant Human HSPB8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket