Recombinant Human BH3 Interacting Domain Death Agonist,GST-tagged
Cat.No. : | BID-1437H |
Product Overview : | Recombinant full-length human BID was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 52kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | BID-1437H |
Description : | BID is a BH3 interacting death domain that heterodimerizes with either agonist BAX or antagonist BCL2. BID is a member of the BCL-2 family of cell death regulators and is a mediator of mitochondrial damage induced by caspase-8 (CASP8). BID initiates apoptosis by binding to regulatory sites on prosurvival BCL2 proteins to directly neutralize their function. Multiple alternatively spliced transcript variants of BID have been found, but the full-length nature of some variants has not been defined. BID together with Cathepsins play an important role in the actions of Camptothecin on breast cancer cells. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | BID BH3 interacting domain death agonist [ Homo sapiens ] |
Synonyms : | BID; BH3 interacting domain death agonist; FP497; MGC15319; MGC42355; p22 BID |
Gene ID : | 637 |
mRNA Refseq : | NM_00119 |
Protein Refseq : | NP_001187 |
MIM : | 601997 |
UniProt ID : | P55957 |
Chromosome Location : | 22q11.2 |
Pathway : | Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Natural killer cell mediated cytotoxicity; Pathways in cancer; p53 signaling pathway; Apoptosis |
Function : | death receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
Bid-711M | Recombinant Mouse Bid Protein, MYC/DDK-tagged | +Inquiry |
Bid-4029M | Active Recombinant Mouse Bid protein(Met1-Asp195), His&GST-tagged | +Inquiry |
BID-2006H | Recombinant Human BID Protein, His-tagged | +Inquiry |
BID-1032M | Recombinant Mouse BID Protein, His (Fc)-Avi-tagged | +Inquiry |
BID-218H | Recombinant Human BID Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BID-8456HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
BID-8455HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket