Recombinant Human DOK1
Cat.No. : | DOK1-28084TH |
Product Overview : | Recombinant full length Human DOK1 with proprietary tag |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 481 amino acids |
Molecular Weight : | 78.980kDa |
Source : | Wheat germ |
Tissue specificity : | Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. |
Biological activity : | useful for Antibody Production and Protein Array |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Reduced glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the DOK family. Type A subfamily.Contains 1 IRS-type PTB domain.Contains 1 PH domain. |
Gene Name : | DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) [ Homo sapiens ] |
Official Symbol : | DOK1 |
Synonyms : | DOK1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); docking protein 1, 62kD (downstream of tyrosine kinase 1); docking protein 1; p62dok; |
Gene ID : | 1796 |
mRNA Refseq : | NM_001197260 |
Protein Refseq : | NP_001184189 |
MIM : | 602919 |
Uniprot ID : | Q99704 |
Chromosome Location : | 2p13 |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; IRS activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; |
Function : | insulin receptor binding; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
DOK1-1590R | Recombinant Rat DOK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DOK1-1375H | Recombinant Human DOK1 Protein, His-tagged | +Inquiry |
DOK1-2813H | Recombinant Human DOK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DOK1-1110H | Recombinant Human DOK1 Protein (1-481 aa), His-SUMO-tagged | +Inquiry |
Dok1-676R | Recombinant Rat Dok1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DOK1-6848HCL | Recombinant Human DOK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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