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Recombinant Human DOK1

Cat.No. : DOK1-28084TH
Product Overview : Recombinant full length Human DOK1 with proprietary tag
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene.
Protein length : 481 amino acids
Molecular Weight : 78.980kDa
Source : Wheat germ
Tissue specificity : Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
Biological activity : useful for Antibody Production and Protein Array
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Reduced glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the DOK family. Type A subfamily.Contains 1 IRS-type PTB domain.Contains 1 PH domain.
Gene Name : DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) [ Homo sapiens ]
Official Symbol : DOK1
Synonyms : DOK1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); docking protein 1, 62kD (downstream of tyrosine kinase 1); docking protein 1; p62dok;
Gene ID : 1796
mRNA Refseq : NM_001197260
Protein Refseq : NP_001184189
MIM : 602919
Uniprot ID : Q99704
Chromosome Location : 2p13
Pathway : B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; IRS activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem;
Function : insulin receptor binding; receptor signaling protein activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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