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Recombinant Human SRC protein, His-tagged

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Cat.No.:
SRC-29696TH
Product Overview:
Recombinant Human SRC fused with His tag at N-terminal was expressed in Insect cells.
Description:
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Source:
Insect cells
Species:
Human
Tag:
His
Form:
25 mM Tris-HCl, pH 8.0, 69 mM NaCl, 1.35 mM KCl, 0.025% Tween-20, 125 mM imidazole, 50% glycerol, and 3 mM DTT
Bio-activity:
205 pmol/min/μg
Molecular Mass:
60.5 kDa
Purity:
> 85%
Applications:
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage:
>6 months at –80 centigrade. Avoid freeze/thaw cycles
Concentration:
1.2 mg/ml


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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