Recombinant Human SYP

• Cat.No.: SYP-31490TH
• Product Overview: Recombinant full length Human Synaptophysin with N terminal proprietary tag; predicted MWt 60.54 kDa inclusive of tag. AAH64550.1

Specification

• Description: This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).
• Protein length: 313 amino acids
• Molecular Weight: 60.540kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAI FAFATCGSYSGELQLNVDCANKTESDLSIEVEFEYPFRLH QVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYS MGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSS AWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDLVT SGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPG APEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDY GQPAGSGGSGYGPQGDYGQQGYGPQGAPTSFSNQM
• Sequence Similarities: Belongs to the synaptophysin/synaptobrevin family.Contains 1 MARVEL domain.

Gene Information

• Gene Name: SYP synaptophysin [ Homo sapiens ]
• Official Symbol: SYP
• Synonyms: SYP; synaptophysin
• Gene ID: 6855
• mRNA Refseq: NM_003179
• Protein Refseq: NP_003170
• MIM: 313475
• Uniprot ID: P08247
• Chromosome Location: Xp11.23-p11.22
• Function: SH2 domain binding; calcium ion binding; cholesterol binding; identical protein binding; syntaxin-1 binding