Recombinant Human THBS1

• Cat.No.: THBS1-31516TH
• Product Overview: Recombinant fragment, corresponding to amino acids 975-1170 of Human Thrombospondin with proprietary tag; 196 amino acids, 48kDa.

Specification

• Description: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the thrombospondin family.Contains 3 EGF-like domains.Contains 1 TSP C-terminal (TSPC) domain.Contains 1 TSP N-terminal (TSPN) domain.Contains 3 TSP type-1 domains.Contains 8 TSP type-3 repeats.Contains 1 VWFC domain.

Gene Information

• Gene Name: THBS1 thrombospondin 1 [ Homo sapiens ]
• Official Symbol: THBS1
• Synonyms: THBS1; thrombospondin 1; thrombospondin-1; THBS; THBS 1; thrombospondin 1p180; TSP; TSP 1; TSP1
• Gene ID: 7057
• mRNA Refseq: NM_003246
• Protein Refseq: NP_003237
• MIM: 188060
• Uniprot ID: P07996
• Chromosome Location: 15q15
• Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem
• Function: calcium ion binding; collagen V binding; eukaryotic cell surface binding; fibrinogen binding; fibroblast growth factor 2 binding