Recombinant Human TNFSF13, FLAG-tagged
Cat.No. : | TNFSF13-2091H |
Product Overview : | Recombinant HumanTNFSF13 Produced inHEK 293 cells. The extracellular domain of human APRIL (aa 88-233) is fused at the N-terminus to human ACRP30headless (aa 16-108) and a FLAG-tag. MW=34kDa (SDS-PAGE). |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNFSF13-2091H |
Description : | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. |
Source : | HEK 293 cells. |
Concentration : | 0.1mg/ml after reconstitution. |
Purity : | ≥95% (SDS-PAGE). |
Formulation : | Lyophilized. Contains PBS. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. |
Specificity : | Binds to human and mouse BCMA and TACI. Binds to proteoglycans. |
Biological Activity : | Stimulates proliferation of serum-starved NIH 3T3 cells. Stimulates B cell proliferation. |
Long Term Storage : | -20°C. |
Handling : | Stable for at least 6 months after receipt when stored at -20°C. |
Stability : | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
Gene Name : | TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 [ Homo sapiens ] |
Synonyms : | TNFSF13; tumor necrosis factor (ligand) superfamily, member 13; APRIL; CD256; TALL2; TRDL-1; ligand; UNQ383/PRO715; TALL-2; TNF-related death ligand 1; a proliferation inducing ligand; a proliferation-inducing ligand; tumor necrosis factor-related death ligand-1; TNF- and APOL-related leukocyte expressed ligand 2; tumor necrosis factor ligand superfamily member 13 epsilon; tumor necrosis factor (ligand) superfamily member 13 transcript variant delta |
Gene ID : | 8741 |
mRNA Refseq : | NM_003808 |
Protein Refseq : | NP_003799 |
MIM : | 604472 |
UniProt ID : | O75888 |
Chromosome Location : | 17p13.1 |
Pathway : | Cytokine-cytokine receptor interaction; Intestinal immune network for IgA production |
Function : | cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding |
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◆ Lysates | ||
TNFSF13-1346MCL | Recombinant Mouse TNFSF13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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