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Official Full Name
autophagy related 5
Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.
May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog;
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ATG5 Related Articles
>> Cai, PP; Wang, HX; et al. Variants of autophagy-related gene 5 are associated with neuromyelitis optica in the Southern Han Chinese population. AUTOIMMUNITY 47:563-566(2014).
>> Cenci, S; et al. Autophagy, a new determinant of plasma cell differentiation and antibody responses. MOLECULAR IMMUNOLOGY 62:289-295(2014).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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