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B2M

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Official Full Name
beta-2-microglobulin
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Synonyms
B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin
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B2M Related Articles
>> Oliveira, AC; de Sevilla, AF; et al. Prospective study of prognostic factors in asymptomatic patients with B-cell chronic lymphocytic leukemia-like lymphocytosis: the cut-off of 11 x 10(9)/L monoclonal lymphocytes better identifies subgroups with different outcomes. ANNALS OF HEMATOLOGY 94:627-632(2015).
>> Park, SJ; Kwon, SG; et al. Selection of appropriate reference genes for RT-qPCR analysis in Berkshire, Duroc, Landrace, and Yorkshire pigs. GENE 558:152-158(2015).

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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