bace1
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  • Official Full Name
  • beta-site APP-cleaving enzyme 1
  • Background
  • Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimers disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
  • Synonyms
  • BACE1; beta-site APP-cleaving enzyme 1; ASP2; BACE; HSPC104; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme;
Cat.#:BACE1-102HTag:GST
Source (Host):Species:Human
Product nameRecombinant Human BACE1, GST-tagged
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Cat.#:BACE1-31HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Beta-Site APP-Cleaving Enzyme 1
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Cat.#:BACE1-1661HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Beta-Site APP-Cleaving Enzyme 1
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Cat.#:BACE1-002HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human BACE1 Protein, Fc-tagged
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Cat.#:BACE1-003HTag:
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human BACE1 Protein
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Cat.#:BACE1-219HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1, C13&N15-labeled
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Cat.#:BACE1-253HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1, Fc tagged
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Cat.#:BACE1-255HTag:None
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1, None tagged
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Cat.#:BACE1-26297THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BACE1
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Cat.#:BACE1-27426THTag:Flag
Source (Host):Species:Human
Product nameRecombinant Human BACE1, FLAG-tagged
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Cat.#:BACE1-713HTag:His & GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BACE1 protein, His & GST-tagged
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Cat.#:BACE1-891HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1, His tagged
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Cat.#:Bace1-252MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Bace1, His tagged
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Cat.#:Bace1-714MTag:His & GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bace1 protein, His & GST-tagged
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Cat.#:Bace1-715RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Bace1 protein, His-tagged
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Cat.#:BACE1-929RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BACE1 Protein
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Cat.#:BACE1-503RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey BACE1 Protein, His-tagged
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Cat.#:BACE1-11726ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BACE1
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Cat.#:BACE1-3006HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1 cell lysate
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Cat.#:BACE1-3102HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1 cell lysate
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Cat.#:BACE1-3103HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BACE1 cell lysate
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Cat.#:BACE1-3077MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BACE1 cell lysate
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Cat.#:CSC-P0539Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 MAb Stable Cell Line-CHO
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Cat.#:CSC-P0540Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 F(ab) Stable Cell Line-CHO
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Cat.#:CSC-P0541Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 scFv Stable Cell Line-CHO
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Cat.#:CSC-P1133Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 MAb Stable Cell Line-CHO
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Cat.#:CSC-P1134Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 F(ab) Stable Cell Line-CHO
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Cat.#:CSC-P1135Tag:
Source (Host):Species:Human
Product nameAnti-Human BACE1 scFv Stable Cell Line-CHO
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BACE1 Related Articles

Sadleir, KR; Eimer, WA; et al. A beta reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level. Molecular Neurodegeneration 10:-(2015).
Yu, YJ; Atwal, JK; et al. Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. SCIENCE TRANSLATIONAL MEDICINE 6:-(2014).