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BAMBI

  • Official Full Name

    BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)

  • Overview

    This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
  • Synonyms

    BAMBI; BMP and activin membrane-bound inhibitor homolog (Xenopus laevis); BMP and activin membrane-bound inhibitor homolog; NMA; BAMBI_HUMAN; BMP and activin membrane bound inhibitor homolog; Non metastatic gene A protein; Non-metastatic gene A protein; Putative transmembrane protein NMA; OTTHUMP00000019384;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Rabbit
  • Wheat Germ
  • C
  • His
  • GST
  • hFc
  • His (Fc)
  • Avi
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BAMBI-75H Recombinant Human BAMBI protein, T7/His-tagged E.coli T7/His
Human BAMBI-3192H Recombinant Human BAMBI protein, His-tagged HEK293 His Met1-Ala152
Human BAMBI-067H Recombinant Human BAMBI protein, GST-tagged Wheat Germ GST
Human BAMBI-2393HCL Recombinant Human BAMBI cell lysate Human Cell N/A
Human BAMBI-1809HF Recombinant Full Length Human BAMBI Protein, GST-tagged In Vitro Cell Free System GST 260 amino acids
Human BAMBI-0134H Recombinant Human BAMBI Protein (Val21-Ala152), C-His-tagged Mammalian cells C-His Val21-Ala152
Human CAB11480RH Rabbit Anti-Human BMP and Activin Membrane-Bound Inhibitor-Like Monoclonal Antibody Rabbit N/A
Human BAMBI-0133H Recombinant Human BAMBI Protein (Arg29-Asp130), N-GST-tagged E.coli N-GST Arg29-Asp130
Mouse Bambi-6868M Recombinant Mouse Bambi protein, His-tagged HEK293 His Met1-Ala152
Mouse Bambi-8686M Recombinant Mouse Bambi protein, hFc-tagged HEK293 hFc Met1-Ala152
Mouse BAMBI-1332MCL Recombinant Mouse BAMBI cell lysate Human Cell N/A
Rat BAMBI-937R Recombinant Rat BAMBI Protein Mammalian Cell His
Rat BAMBI-595R Recombinant Rat BAMBI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat BAMBI-595R-B Recombinant Rat BAMBI Protein Pre-coupled Magnetic Beads HEK293
Chicken BAMBI-4133C Recombinant Chicken BAMBI Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BAMBI Related Articles
  • BAMBI Related Research Area

BAMBI involved in several pathways and played different roles in them. We selected most pathways BAMBI participated on our site, such as Wnt signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BAMBI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayTRP53;BAMBIB;NFATC1;FBXW11;RAC1;TBL1XR1;SFRP1A;PRKACAB;PRKACBA
TGF-beta signaling pathwayBMP8B;ACVR2B;ACVR1BA;PPP2CB;LFT2;ACVR1L;TFDP1A;SMAD3;CHRD

BAMBI has several biochemical functions, for example, frizzled binding, type II transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BAMBI itself. We selected most functions BAMBI had, and list some proteins which have the same functions with BAMBI. You can find most of the proteins on our site.

Function Related Protein
frizzled bindingWNT3A;DVL3A;WNT7B;FZD1;WNT6;WNT9A;CTHRC1;WNT11R;RNF43
type II transforming growth factor beta receptor bindingENG;TGFB1;TGFBR1;TGFBR3;BAMBI;TGFB1A;TGFB3;TGFB2

BAMBI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BAMBI here. Most of them are supplied by our site. Hope this information will be useful for your research of BAMBI.

DVL2; LRP6; FZD5; SEP15; SOX30

Jin, Y; Wan, Y; et al. Treg/IL-17 Ratio and Treg Differentiation in Patients with COPD. PLOS ONE 9:-(2014).
Le Bras, GF; Loomans, HA; et al. Activin A balance regulates epithelial invasiveness and tumorigenesis. LABORATORY INVESTIGATION 94:1134-1146(2014).
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