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BCAT2

  • Official Full Name

    branched chain amino-acid transaminase 2, mitochondrial

  • Overview

    This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    BCAT2; branched chain amino-acid transaminase 2, mitochondrial; BCT2, branched chain aminotransferase 2, mitochondrial; branched-chain-amino-acid aminotransferase, mitochondrial; BCAM; mitochondrial; BCAT 2; BCAT(m); BCAT2_HUMAN; BCATM; BCT2; Branched chain aminotransferase 2, mitochondrial; Branched-chain-amino-acid aminotransferase; ECA40; Placental protein 18; PP18;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • His|Myc
  • His|T7
  • SUMO
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BCAT2-15863H Recombinant Human BCAT2, His-tagged E.coli His 28-392aa
Human BCAT2-10170H Recombinant Human BCAT2, His-tagged E.coli His 41-392a.a.
Human BCAT2-1962H Recombinant Human Branched Chain Amino-Acid Transaminase 2, Mitochondrial, His-tagged E.coli His
Human BCAT2-130H Recombinant Human BCAT2 Protein, GST-tagged Wheat Germ GST
Human BCAT2-162HCL Recombinant Human BCAT2 cell lysate N/A
Human BCAT2-575HFL Recombinant Full Length Human BCAT2 Protein, C-Flag-tagged Mammalian cells Flag
Human BCAT2-1609HF Recombinant Full Length Human BCAT2 Protein, GST-tagged In Vitro Cell Free System GST 392 amino acids
Human BCAT2-2366H Recombinant Human BCAT2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BCAT2-2578H Recombinant Human BCAT2 protein, His-SUMO-tagged E.coli His-SUMO 28-392aa
Human BCAT2-0411H Recombinant Human BCAT2 Protein (Ala107-Val392), N-His-tagged E.coli N-His Ala107-Val392
Human BCAT2-0246H Recombinant Human BCAT2 Protein (A28-V392), Tag Free E.coli No tag A28-V392
Human BCAT2-672H Recombinant Human BCAT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BCAT2-433H Recombinant Human BCAT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human BCAT2-0247H Recombinant Human BCAT2 Protein (A28-V392), His/Strep tagged E.coli His/Strep A28-V392
Human BCAT2-433H-B Recombinant Human BCAT2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Bcat2-302M Recombinant Mouse Bcat2 Protein, His-tagged E.coli N-His Ile223-Val393
Mouse BCAT2-2559M Recombinant Mouse BCAT2 Protein (28-393 aa), His-Myc-tagged E.coli His/Myc 28-393 aa
Mouse Bcat2-694M Recombinant Mouse Bcat2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Bcat2-1038R Recombinant Rat Bcat2 protein, His & T7-tagged E.coli His/T7 Phe218~Val393 (Accession # O35854)
Rat BCAT2-952R Recombinant Rat BCAT2 Protein Mammalian Cell His
Rat BCAT2-610R-B Recombinant Rat BCAT2 Protein Pre-coupled Magnetic Beads HEK293
Rat BCAT2-610R Recombinant Rat BCAT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish BCAT2-783Z Recombinant Zebrafish BCAT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BCAT2 involved in several pathways and played different roles in them. We selected most pathways BCAT2 participated on our site, such as Cysteine and methionine metabolism, Valine, leucine and isoleucine degradation, Valine, leucine and isoleucine biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCAT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cysteine and methionine metabolismLDHBB;LDHB;CBS;CDO1;GCLM;DNMT3B;MDH1AA;CBSB;DNMT4
Valine, leucine and isoleucine degradationACADS;IL4I1;OXCT2B;AACS;ALDH2.2;MCCC2;HIBADHB;ALDH3A2;OXCT1B
Valine, leucine and isoleucine biosynthesisBCAT1;BCAT2
Pantothenate and CoA biosynthesisPANK1;PPCS;PPCDC;DPYS;UPB1;PANK1B;VNN1;ENPP1;AASDHPPT
Metabolic pathwaysCOX5B;AOC2;GPI1;B3GNT1;POLR1B;ALOX12;NT5C1B;PTGES3B;FECH
-Oxocarboxylic acid metabolismBCAT1;IDH3A;ACO2;BCAT2;GPT;GOT2B;ACY1;IDH2;IDH1
Biosynthesis of amino acidsPFKMB;IDH1;PRPS1A;IDH2;GLULA;IDH3G;PKLR;AADAT;THA1

BCAT2 has several biochemical functions, for example, L-isoleucine transaminase activity, L-leucine transaminase activity, L-valine transaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BCAT2 itself. We selected most functions BCAT2 had, and list some proteins which have the same functions with BCAT2. You can find most of the proteins on our site.

Function Related Protein
L-isoleucine transaminase activityBCAT2;BCAT1
L-leucine transaminase activityBCAT2;BCAT1
L-valine transaminase activityBCAT1;BCAT2
branched-chain-amino-acid transaminase activityBCAT1;BCAT2

BCAT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCAT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCAT2.

CREB3; ALDOA; PTGDS

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