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Official Full Name
B-Cell CLL/Lymphoma 2
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
BCL2; B-cell CLL/lymphoma 2; Bcl-2; apoptosis regulator Bcl-2
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BCL2 Related Articles
>> Marguet, F; Bergogne, L; et al. Fetal presentation of congenital fibrosarcoma of the meninges: case report and literature review. CLINICAL NEUROPATHOLOGY 34:70-75(2015).
>> Abdel-Latif, M; Sakran, T; et al. Immunomodulatory effect of diethylcarbamazine citrate plus filarial excretory-secretory product on rat hepatocarcinogenesis. INTERNATIONAL IMMUNOPHARMACOLOGY 24:173-181(2015).

45-16 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269
Europe: 44-207-048-3343
FAX: 1-631-938-8127

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