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Official Full Name
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription.
TFC5; TFNR; TAF3B1; TFIIIB; TFIIIB90; HSA238520; TFIIIB150