BLMH
-
Official Full Name
bleomycin hydrolase
-
Overview
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. -
Synonyms
BLMH; bleomycin hydrolase; BH; BLM hydrolase; BMH; EC 3.4.22.40;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | BLMH-242H | Recombinant Human BLMH Protein, GST-tagged | Wheat Germ | GST | ||
Human | BLMH-802H | Recombinant Human Bleomycin Hydrolase, His-tagged | E.coli | His | ||
Human | BLMH-26114TH | Recombinant Human BLMH, His-tagged | E.coli | His | 475 amino acids | |
Human | BLMH-1155H | Recombinant Human BLMH, His tagged | E.coli | His | ||
Human | BLMH-243H | Recombinant Human BLMH Protein, GST-tagged | Wheat Germ | GST | ||
Human | BLMH-26116TH | Recombinant Human BLMH, His-tagged | E.coli | His | ||
Human | BLMH-8445HCL | Recombinant Human BLMH 293 Cell Lysate | HEK293 | N/A | ||
Human | BLMH-418H | Recombinant Human BLMH Protein, His-tagged | E.coli | His | Met213~Trp447 | |
Human | BLMH-1648HF | Recombinant Full Length Human BLMH Protein, GST-tagged | In Vitro Cell Free System | GST | 455 amino acids | |
Human | BLMH-0765H | Recombinant Human BLMH Protein (Met213-Trp447), His tagged | E.coli | His | Met213-Trp447 | |
Mouse | Blmh-1190M | Recombinant Mouse Blmh, His tagged | E.coli | His | ||
Mouse | BLMH-2416M | Recombinant Mouse BLMH Protein | Mammalian Cell | His | ||
Mouse | BLMH-1041M-B | Recombinant Mouse BLMH Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Blmh-419M | Recombinant Mouse Blmh Protein, His-tagged | E.coli | His | Ala27~Cys164 | |
Mouse | BLMH-1041M | Recombinant Mouse BLMH Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | Blmh-420R | Recombinant Rat Blmh Protein, His-tagged | E.coli | His | Val30~Phe165 | |
Zebrafish | BLMH-10377Z | Recombinant Zebrafish BLMH | Mammalian Cell | His | ||
Chicken | BLMH-6661C | Recombinant Chicken BLMH | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- BLMH Related Articles
- BLMH Related Research Area
BLMH involved in several pathways and played different roles in them. We selected most pathways BLMH participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BLMH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Adaptive Immune System | RNF41;KLRB1F;KIF26A;SIGLEC9;SEC61B;DCTN2;KLC3;RAET1E;DYNC1LI2 |
Antigen processing: Ubiquitination & | TPP2;RNF6;RNF41;UBR2;ASB8;SH3RF1;TRIM63;UBE2V2;UFL1 |
Proteasome degradation | UCHL3;RNF34;PJA1;ASB10;WWP1;LTN1;RNF182;SH3RF1;ASB17 |
Class I MHC mediated antigen processing & | ASB13;TPP2;UBE2U;ASB2;PJA1;RNF25;MKRN1;ASB7;RNF41 |
presentation | UBE2F;SEC24A;RNF138;WWP1;SEC61B;CMTM2A;RNF19B;LRRC41;PJA1 |
Immune System | GRAP2A;CD200R4;PAG1;RNF216;NCKIPSD;ADAR;FCN1;LRRFIP1;OSBPL1A |
BLMH has several biochemical functions, for example, aminopeptidase activity, carboxypeptidase activity, cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BLMH itself. We selected most functions BLMH had, and list some proteins which have the same functions with BLMH. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
aminopeptidase activity | LTA4H;NPEPL1;ERAP2;RNPEP;Ctsl;ERAP1;XPNPEP1;DPP9;TRHDE |
carboxypeptidase activity | CNDP1;PGCP;NAALADL1;CPB1;CPA2;CPM;CPD;ACE;BLMH |
cysteine-type endopeptidase activity | CFLARA;USP24;UCHL1;Casp3;USP34;USP12A;USP49;CTSF;CTSSA |
cysteine-type peptidase activity | CAPN2;FAM49BA;SENP3A;ESPL1;CLCA3;USP43A;CTSLA;CLCA5;CTSK |
protein binding | NXT2;TLE3;FAM131C;EDNRB;YY1AP1;IMP3;SLC5A1;NBR1;SHC4 |
BLMH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BLMH here. Most of them are supplied by our site. Hope this information will be useful for your research of BLMH.
WDYHV1; NUDT12; APP; Fam134a; USP53; PDPK1; TRIO; CYP2C8; KBTBD7; ECSIT; RNF32; MAST1; Ckap5
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All BLMH Products
Required fields are marked with *
My Review for All BLMH Products
Required fields are marked with *