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BRSK2

  • Official Full Name

    BR serine/threonine kinase 2

  • Overview

    Brain-specific kinase 1 (BRSK1; SAD-B) and Brain-specific kinase 2 (BRSK2; SAD-A) are serine/threonine kinases closely related to AMPK. LKB1 phosphorylates Thr189 in the T-loop of BRSK1 and Thr174 in the T-loop of BRSK2, resulting in activation of the kin
  • Synonyms

    BRSK2; BR serine/threonine kinase 2; C11orf7, chromsosome 11 open reading frame 7 , STK29; serine/threonine-protein kinase BRSK2; PEN11B; serine/threonine kinase 29; protein kinase SAD1B; brain-selective kinase 2; serine/threonine-protein kinase 29; BR s;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BRSK2-257H Active Recombinant Human BRSK2, GST-tagged Sf9 Insect Cell GST
Human BRSK2-31H Active Recombinant Human BRSK2(2-end) Protein, N-His-tagged Sf21 His 2-end
Human BRSK2-350H Recombinant Human BRSK2 Protein, GST-tagged Sf21 Insect Cell GST
Human BRSK2-505H Recombinant Human BR Serine/Threonine Kinase 2, His-tagged Insect Cell His
Human BRSK2-26106TH Recombinant Human BRSK2, His-tagged His
Human BRSK2-351H Recombinant Human BRSK2 Protein, GST-tagged Wheat Germ GST
Human BRSK2-8403HCL Recombinant Human BRSK2 293 Cell Lysate HEK293 N/A
Human BRSK2-301152H Recombinant Human BRSK2 protein, GST-tagged E.coli GST Met482-Leu649
Human BRSK2-1172H Recombinant Human BRSK2 Protein (T2-P736), Tag Free Insect Cell No tag T2-P736
Human BRSK2-3811HF Recombinant Full Length Human BRSK2 Protein, GST-tagged In Vitro Cell Free System GST 170 amino acids
Human BRSK2-4834H Recombinant Human BRSK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BRSK2-8365HF Active Recombinant Full Length Human BRSK2 Protein, GST-tagged Insect (sf21) GST 1-674(end)
Human BRSK2-1173H Recombinant Human BRSK2 Protein (T2-P736), GST tagged Insect Cell GST T2-P736
Mouse BRSK2-2502M Recombinant Mouse BRSK2 Protein Mammalian Cell His
Mouse Brsk2-1895M Recombinant Mouse Brsk2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BRSK2-1094M-B Recombinant Mouse BRSK2 Protein Pre-coupled Magnetic Beads HEK293
Mouse BRSK2-1094M Recombinant Mouse BRSK2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken BRSK2-4411C Recombinant Chicken BRSK2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BRSK2 involved in several pathways and played different roles in them. We selected most pathways BRSK2 participated on our site, such as Bile acid and bile salt metabolism, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRSK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Bile acid and bile salt metabolismCYP27A1;NCOA2;ACOT8;Alb;SCP2B;CYP7A1;CYP46A1;SLCO1B1;AKR1C2
MetabolismCKBA;ARL2BP;DIO2;PDK3B;ITPKB;AK7;GSTK1;FABP11B;MED25
Metabolism of lipids and lipoproteinsPIK3R6;APOA5;ARV1;INSIG2;CPT2;CYP2U1;PPM1L;GLIPR1;FABP11B
Primary bile acid biosynthesisCH25HL2;HSD3B7;CYP46A1.2;SCP2A;CYP46A1.4;CH25H;AKR1D1;SLC27A5;CYP7B1
Synthesis of bile acids and bile saltsSLC27A2A;SCP2B;AKR1C2;BRSK2

BRSK2 has several biochemical functions, for example, cholesterol 25-hydroxylase activity, iron ion binding, steroid hydroxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BRSK2 itself. We selected most functions BRSK2 had, and list some proteins which have the same functions with BRSK2. You can find most of the proteins on our site.

Function Related Protein
cholesterol 25-hydroxylase activityBRSK2;CH25H
iron ion bindingBRSK2;TPH1A;ALOX15B;CYP21A1;TMEM195;CYP1D1;OGFOD1;TPH1;CYGB2
steroid hydroxylase activityCYP2V1;CYP46A1.2;CYP2W1;CYP2AD3;CYP2K17;CYP2AA4;CYP2K18;CYP2C50;CYP2X8

BRSK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRSK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRSK2.

KBTBD7; Rrbp1

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