cd33
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  • Official Full Name
  • CD33 CD33 molecule
  • Background
  • CD33 is a 67-kDa transmembrane glycoprotein that contains one V-set and one C2-set Ig-like domain6. It is a biomarker and therapeutic target for acute myeloid leukemia (AML). The recruitment of SHP-1 and SHP-2 by CD33 results in inhibition of tyrosine phosphorylation and Ca2+ mobilization. CD33 expression is assumed to be restricted to the myeloid lineage of immune cells. Thus, it is highly expressed on myeloid-committed cells of the bone marrow and circulating monocytes. CD33 expression is down-regulated to low levels on peripheral granulocytes and resident macrophages, and it is constitutive on DC. This expression pattern suggests a role of CD33 on myeloid differentiation and cellular function of monocyte and DC
  • Synonyms
  • CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3
Cat.#:CD33-0790HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD33 Protein
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Cat.#:CD33-0791HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD33 Protein, GST-Tagged
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Cat.#:CD33-459HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33 Molecule, Fc Chimera
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Cat.#:CD33-10946HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD33, GST-tagged
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Cat.#:CD33-176HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CD33, Fc Chimera
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Cat.#:CD33-234HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33, His tagged
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Cat.#:CD33-267HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33, His-tagged, Biotinylated
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Cat.#:CD33-268HTag:His & Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33 Protein, His & Avi-tagged, Biotinylated
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Cat.#:CD33-313HTag:None
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33, Fc tagged
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Cat.#:CD33-487HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD33 molecule, His-tagged
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Cat.#:CD33-5088HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD33, His-tagged
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Cat.#:CD33-675HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human CD33, Fc-tagged, Biotinylated
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Cat.#:CD33-7815HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33 protein, His-tagged
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Cat.#:CD33-833HTag:Fc/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CD33 Protein, Fc/His-tagged
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Cat.#:Cd33-5169MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd33, His tagged
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Cat.#:Cd33-586MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cd33 protein, His-tagged
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Cat.#:Cd33-6889MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD33 Antigen, Fc-tagged
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Cat.#:CD33-181CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CD33, His-tagged
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Cat.#:CD33-912HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33 cell lysate
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Cat.#:CD33-978HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD33 cell lysate
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Cat.#:CD33-1808MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD33 cell lysate
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Cat.#:CD33-1829MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CD33 cell lysate
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CD33 Related Articles

Loke, J; Khan, JN; et al. Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia. ANNALS OF HEMATOLOGY 94:361-373(2015).
Xu, LM; Zhang, Y; et al. Bi-specific antibodies with high antigen-binding affinity identified by flow cytometry. INTERNATIONAL IMMUNOPHARMACOLOGY 24:463-473(2015).