cfh
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  • Official Full Name
  • complement factor H
  • Background
  • Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at a concentration of 500–800 micrograms per milliliter). Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens and does not damage host tissue. Factor H regulates complement activation on self cells by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3 convertase, C3bBb. Factor H protects self cells from complement activation but not bacteria/viruses, in that it binds to glycosaminoglycans (GAGs) that are present on host cells but not pathogen cell surfaces.
  • Synonyms
  • CFH; complement factor H; beta-1H; factor H-like 1; beta-1-H-globulin; OTTHUMP00000033598; OTTHUMP00000034106; H factor 1 (complement); H factor 2 (complement); adrenomedullin binding protein; isoform b ag; e-related maculopathy susceptibility 1; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; MGC88246; age-related maculopathy susceptibility 1
Cat.#:CFH-26763THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CFH, His-tagged
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Cat.#:CFH-3183HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CFH, His tagged
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Cat.#:CFH-641HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CFH protein, His-tagged
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Cat.#:Cfh-392MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cfh protein, His-tagged
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Cat.#:Cfh-396MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cfh protein, Fc-tagged
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Cat.#:Cfh-626MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Cfh Protein, His-tagged
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Cat.#:Cfh-642MTag:His & T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cfh protein, His & T7-tagged
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Cat.#:Cfh-643RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cfh protein, His-tagged
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Cat.#:CFH-7847ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CFH
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Cat.#:CFH-640CTag:His & T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle CFH protein, His & T7-tagged
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Cat.#:CFH-115HTag:
Source (Host):Human SerumSpecies:Human
Product nameNative Human Factor H
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Cat.#:CFH-23HTag:
Source (Host):Human SerumSpecies:Human
Product nameNative Human Complement factor H
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Cat.#:CFH-2409HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CFH cell lysate
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CFH Related Articles

Cortina, G; Trojer, R; et al. De novo tacrolimus-induced thrombotic microangiopathy in the early stage after renal transplantation successfully treated with conversion to everolimus. PEDIATRIC NEPHROLOGY 30:693-697(2015).
Khandelwal, P; Gupta, A; et al. Effect of plasma exchange and immunosuppressive medications on antibody titers and outcome in anti-complement factor H antibody-associated hemolytic uremic syndrome. PEDIATRIC NEPHROLOGY 30:451-457(2015).