CSF3
-
Official Full Name
Colony Stimulating Factor 3 (Granulocyte) -
Overview
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. -
Synonyms
CSF3;GCSF;CSF3OS;C17orf33;MGC45931;granulocyte colony-stimulating factor;filgrastim;lenograstim;pluripoietin;OTTHUMP00000164325;OTTHUMP00000164326;OTTHUMP00000164327;OTTHUMP00000164328
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rat
- Rhesus macaque
- Zebrafish
- Cattle
- Pig
- Dog
- E.coli
- Yeast
- HEK293
- Barley Grain
- Pseudomonas Fluorescens
- P.pastoris
- Mammalian Cells
- CHO
- Wheat Germ
- Rhesus Macaque
- Human Cells
- Rabbit
- In Vitro Cell Free System
- Rat
- Non
- Fc
- His
- S
- GST
- T7
- DDK
- Myc
- Avi
- MBP
- SUMO
Involved Pathway
CSF3 involved in several pathways and played different roles in them. We selected most pathways CSF3 participated on our site, such as Cytokine-cytokine receptor interaction,Cytokines and Inflammatory Response,Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PI3K-Akt signaling pathway | SGK2,CHAD,CSF1R,EFNA4,PRP2,CSH,CSF1,LAMC3,EFNA2,PIK3AP1 |
| Cytokines and Inflammatory Response | CSF2,CSF1 |
| Malaria | KLRB1,TGFB3,IL18,THBS4,TLR2,IL-8,HBB-B1,ICAM1,CD81,DARC |
| Cytokine-cytokine receptor interaction | CLCF1,TGFB2,IL5,EDA2R,IL9R,IL19,IFNA17,TP-1,IFNPHI1,CCL20B |
| Jak-STAT signaling pathway | Il4ra,HRASA,IL23,PRLRA,IL22,PTPN11A,IFNA21,IL12RB2,PIAS4B,TP-1 |
| Hematopoietic cell lineage | KITLG,ITGB3,HLA-DRB1,FCER2,MME,ITGA6,FCGR1A,CD34,CD22,CSF1R |
Protein Function
CSF3 has several biochemical functions, for example, cytokine activity,enzyme binding,granulocyte colony-stimulating factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF3 itself. We selected most functions CSF3 had, and list some proteins which have the same functions with CSF3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | LTA,IL23,GM13279,CMTM6,IL17B,IL29,TNFSF13B,SCG2,IFNA8,IL36B |
| growth factor activity | VEGFAA,FGF20A,GDF15,TGFB1,GH1,MIA1,IL34,FBRS,FGF18A,IL7 |
| enzyme binding | TSPAN10,GOLPH3,RCOR3,RCOR1,YWHAE,CDC20,EIF4E,APOA5,HAND2,PTEN |
Interacting Protein
CSF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF3.
Resources
Gene Families
Related Services
Related Products
References
- Chen, XJ; Lu, J; et al. Cytokines in osteoblast-conditioned medium promote the migration of breast cancer cells. TUMOR BIOLOGY 35:791-798(2014).
- Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).
