dck
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  • Official Full Name
  • deoxycytidine kinase
  • Background
  • Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs.Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents.Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives.DCK is clinically important because of its relationship to drug resistance and sensitivity.
  • Synonyms
  • DCK; deoxycytidine kinase; DCK protein; DCK_HUMAN; OTTHUMP00000160356; OTTHUMP00000219118; OTTHUMP00000219119; deoxynucleoside kinase
Cat.#:DCK-2390HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DCK Protein, GST-tagged
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Cat.#:DCK-2265BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis DCK protein, His-tagged
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Cat.#:DCK-11853HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCK, GST-tagged
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Cat.#:DCK-185HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCK protein
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Cat.#:DCK-27365THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCK, His-tagged
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Cat.#:DCK-795HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Deoxycytidine Kinase, His-tagged
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Cat.#:DCK-796HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DCK, His-tagged
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Cat.#:DCK-857HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human DCK Protein, DDK-tagged
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Cat.#:DCK-4349MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DCK Protein
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Cat.#:DCK-1793RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DCK Protein
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Cat.#:DCK-1191RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DCK Protein, His-tagged
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Cat.#:DCK-1591CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DCK
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Cat.#:DCK-1626ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DCK
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Cat.#:DCK-7051HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DCK 293 Cell Lysate
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Cat.#:Kit-0879Tag:
Source (Host):Species:
Product namedCK Screening Assay Kit
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DCK Related Articles

Zhuang, XM; Deng, JT; et al. Metabolism of novel anti-HIV agent 3-cyanomethyl-4-methyl-DCK by human liver microsomes and recombinant CYP enzymes. ACTA PHARMACOLOGICA SINICA 32:1276-1284(2011).
Fong, WF; Shen, XL; et al. Methoxylation of 3 ',4 '-aromatic side chains improves P-glycoprotein inhibitory and multidrug resistance reversal activities of 7,8-pyranocoumarin against cancer cells. BIOORGANIC & MEDICINAL CHEMISTRY 16:3694-3703(2008).