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DECR1

  • Official Full Name

    2,4-dienoyl CoA reductase 1, mitochondrial

  • Overview

    This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters.
  • Synonyms

    DECR1; 2,4-dienoyl CoA reductase 1, mitochondrial; DECR; 2,4-dienoyl-CoA reductase, mitochondrial; SDR18C1; short chain dehydrogenase/reductase family 18C; member 1; 4-enoyl-CoA reductase; short chain dehydrogenase/reductase family 18C, member 1; NADPH;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DECR1-971H Recombinant Human 2,4-Dienoyl-CoA Reductase, Mitochondrial, His-tagged E.coli His
Human DECR1-26259TH Recombinant Human DECR1, His-tagged E.coli His 301 amino acids
Human DECR1-973H Recombinant Human DECR1, GST-tagged Wheat Germ GST
Human DECR1-972H Recombinant Human DECR1, His-tagged E.coli His
Human DECR1-26H Recombinant Human DECR1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DECR1-6997HCL Recombinant Human DECR1 293 Cell Lysate HEK293 N/A
Human DECR1-733H Recombinant Human DECR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Decr1-2516M Recombinant Mouse Decr1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Cynomolgus Monkey DECR1-459C Recombinant Cynomolgus DECR1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey DECR1-205C Recombinant Cynomolgus Monkey DECR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey DECR1-205C-B Recombinant Cynomolgus Monkey DECR1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DECR1-576Z Recombinant Zebrafish DECR1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DECR1 Related Articles

DECR1 involved in several pathways and played different roles in them. We selected most pathways DECR1 participated on our site, such as Fatty Acid Beta Oxidation, Fatty Acid Biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DECR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty Acid Beta OxidationCPT1B;SLC25A20;CPT2;CHKB;ECI1;CRAT;CPT1A;DECR1
Fatty Acid BiosynthesisACSL4B;ACSBG1;ACSL1;FASN;ACSL5;OLAH;ECH1;ECHDC3;ACSL3A
Fatty acid, triacylglycerol, and ketone body metabolismMED20;MED6;MED10;APOA5;Agmo;ACOT12;MED19;GPAT2;MED22
MetabolismTM9SF1;DDAH2;CPT2;MAPK1IP1L;SLC25A2;CYP8B2;PPARGC1B;SLC25A1A;ADHFE1
Metabolism of lipids and lipoproteinsGDF1;CYP8B2;PTGR1;PIK3R6;ACOT11;VAPB;CDK19;PPP1R2;Agmo
Mitochondrial Fatty Acid Beta-OxidationDECR1;ECI1;ACAD11
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids

DECR1 has several biochemical functions, for example, 2,4-dienoyl-CoA reductase (NADPH) activity, NADPH binding, oxidoreductase activity, acting on NAD(P)H. Some of the functions are cooperated with other proteins, some of the functions could acted by DECR1 itself. We selected most functions DECR1 had, and list some proteins which have the same functions with DECR1. You can find most of the proteins on our site.

Function Related Protein
2,4-dienoyl-CoA reductase (NADPH) activityDECR1;DECR2
NADPH bindingDHFR;CBR4;TP53I3;CRYZ;CBR3;HMGCR;QDPR;DECR1;GRHPR
oxidoreductase activity, acting on NAD(P)HWDR93;AIFM1;NDUFS8A;ECSIT;NDUFS8B;DECR1;MIOX;DERL3

DECR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DECR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DECR1.

PTTG1; thiI; ssrna_au; Ktn1; NOP56; CCDC22; AK1; ESR1; NPM1; VCAM1; NSS; RPL10; JAK3; MSH6

Filppula, SA; Yagi, AI; et al. Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase from rat liver - Molecular characterization. JOURNAL OF BIOLOGICAL CHEMISTRY 273:349-355(1998).
KajiharaKano, H; Hayakari, M; et al. Characterization of S-hexylglutathione-binding proteins of human hepatocellular carcinoma: separation of enoyl-CoA isomerase from an Alpha class glutathione transferase form. BIOCHEMICAL JOURNAL 328:473-478(1997).
  • Q&As
  • Reviews

Q&As (7)

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How does DECR1 interact with other enzymes in the fatty acid oxidation pathway? 06/23/2023

DECR1 works alongside other enzymes in β-oxidation, ensuring effective fatty acid degradation.

What role does DECR1 play in energy production and mitochondrial function? 06/08/2023

DECR1 plays a role in energy production by aiding in the efficient processing of fatty acids in mitochondria.

How do genetic variations in the DECR1 gene affect metabolic processes and disease susceptibility? 02/08/2022

Mutations in DECR1 can impact fatty acid metabolism, potentially leading to metabolic disorders.

How does DECR1 contribute to the breakdown of unsaturated fatty acids? 02/18/2021

It specifically catalyzes the reduction of double bonds in unsaturated fatty acids, facilitating their breakdown.

What is the impact of altered DECR1 activity on metabolic disorders such as diabetes or obesity? 10/02/2018

Altered DECR1 activity can affect energy balance and fat metabolism, influencing conditions like diabetes and obesity.

What potential therapeutic applications could arise from targeting DECR1 in metabolic diseases? 03/26/2018

Targeting DECR1 could offer new treatment avenues for managing metabolic conditions like obesity and diabetes.

What is the primary function of DECR1 in fatty acid metabolism? 05/04/2017

DECR1, or 2,4-dienoyl-CoA reductase 1, is key in the metabolism of unsaturated fatty acids, particularly in β-oxidation.

Customer Reviews (3)

Write a review
Reviews
10/29/2022

    Invaluable support. Crucial for protein experiments.

    07/12/2022

      Key to credibility. Enhances research credibility.

      10/12/2019

        Swift and accurate. An asset to our research.

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