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GIMAP1

Official Full Name

GTPase, IMAP family member 1
Overview

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene.
Synonyms

GIMAP1; GTPase, IMAP family member 1; GTPase IMAP family member 1; HIMAP1; IMAP1; IMAP38; immunity associated protein 1;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GIMAP1-5939HCL	Recombinant Human GIMAP1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GIMAP1-2908H	Recombinant Human GIMAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Gimap1-3207M	Recombinant Mouse Gimap1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mus musculus (Mouse)	RFL34807MF	Recombinant Full Length Mouse Gtpase Imap Family Member 1(Gimap1) Protein, His-Tagged	E.coli expression system	His	Full Length (1-277)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
GIMAP1 Related Articles

GIMAP1 involved in several pathways and played different roles in them. We selected most pathways GIMAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GIMAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GIMAP1 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP1 itself. We selected most functions GIMAP1 had, and list some proteins which have the same functions with GIMAP1. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	DNM2;RAB1BA;TUBB5;RHOGC;LRRK2;TUFM;EEF2B;RRAGB;RND3A

GIMAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIMAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIMAP1.

Webb, LMC; Bell, SE; et al. Critical role for GIMAP1 in the germinal centre reaction. IMMUNOLOGY 143:66-66(2014).

Webb, LMC; Pascall, JC; et al. Generation and Characterisation of Mice Deficient in the Multi-GTPase Domain Containing Protein, GIMAP8. PLOS ONE 9:-(2014).