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IKZF4

Official Full Name

IKAROS family zinc finger 4 (Eos)
Overview

Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.
Synonyms

IKZF4; IKAROS family zinc finger 4 (Eos); zinc finger protein, subfamily 1A, 4 (Eos) , ZNFN1A4; zinc finger protein Eos; Eos; Eos protein; IKAROS family zinc finger 4; Ikaros family zinc finger protein 4; IKZF4_HUMAN; KIAA1782; Zinc finger protein Eos (IKAROS family zinc finger protein 4); ZNFN1A4; OTTHUMP00000243022; OTTHUMP00000243025; OTTHUMP00000243026; zinc finger transcription factor Eos; zinc finger protein, subfamily 1A, 4 (Eos);

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	IKZF4-851HCL	Recombinant Human IKZF4 cell lysate		N/A	Inquiry
Mouse	IKZF4-8107M	Recombinant Mouse IKZF4 Protein	Mammalian Cell	His	Inquiry
Mouse	IKZF4-4489M	Recombinant Mouse IKZF4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	IKZF4-4489M-B	Recombinant Mouse IKZF4 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

IKZF4 involved in several pathways and played different roles in them. We selected most pathways IKZF4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IKZF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

IKZF4 has several biochemical functions, for example, bHLH transcription factor binding, metal ion binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IKZF4 itself. We selected most functions IKZF4 had, and list some proteins which have the same functions with IKZF4. You can find most of the proteins on our site.

Function	Related Protein
bHLH transcription factor binding	SIRT1;RUNX2;SOX9;TCF3B;BHLHE40;TCF12;PSMD9;TWIST1;HAND1
metal ion binding	GDPD2;ZFP330;GPHN;HBAA1;NQO2;ZHX3;ALKBH5;PMM1;ZNF383
protein heterodimerization activity	BMP7A;TYRO3;RAF1;ABCG8;CEBPE;NFYC;GUCY1A3;SYT5;PHC2B
protein homodimerization activity	PDK2;DCK;TFRC;IDE;SH3GLB1;CCDC103;PFKM;NR0B1;TKT
sequence-specific DNA binding	THRB;EN1;ZNF35;SIX1;NKX2-1;NR2F1B;NANOG;ZNF148;MTA3
transcription factor activity, sequence-specific DNA binding	GTF2H2;KCNA3;ZNF397;SRF;HOXB8B;PLAG1;POU5F3;POU6F2;FOXQ2
transcription regulatory region DNA binding	SOX5;SOX2;NKX2;SALL1A;ATF5;MTERFD1;TAF7L;HNF4A;PRDM5

IKZF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IKZF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IKZF4.

NFKBIA; FHL2