IMPAD1
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Official Full Name
inositol monophosphatase domain containing 1
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Synonyms
IMPAD1; inositol monophosphatase domain containing 1; inositol monophosphatase 3; FLJ20421; IMPA3; IMP 3; IMPase 3; Inositol monophosphatase domain containing protein 1; Myo inositol monophosphatase A3; OTTHUMP00000226649; golgi-resident PAP phosphatase; myo-inositol monophosphatase A3; inositol-1(or 4)-monophosphatase 3; inositol monophosphatase domain-containing protein 1; Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase; GPAPP;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Callithrix jacchus (White-tufted-ear marmoset)
- Danio rerio (Zebrafish) (Brachydanio rerio)
- Human
- Mouse
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- Xenopus laevis (African clawed frog)
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Zebrafish
- CHO
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- IMPAD1 Related Articles
- IMPAD1 Related Research Area
IMPAD1 involved in several pathways and played different roles in them. We selected most pathways IMPAD1 participated on our site, such as Inositol phosphate metabolism, Sulfur metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMPAD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | MIOX;SYNJ2;MTM1;PI4K2B;PIP5K1AB;INPP5K;NUDT4A;PLCD3A;ITPK1 |
| Sulfur metabolism | IMPAD1;cysH;PAPSS2B;CYCS;PAPSS2;BPNT1;ETHE1;TST;MPST |
| Metabolic pathways | PPAP2B;ATP6V1G1;BDH1;IL4I1;SPTLC2B;DAO.3;ASL2;MGAT4A;GMPPAB |
| Phosphatidylinositol signaling system | PIP5K1A;MTMR4;IMPAD1;MTMR7;INPP4A;IPMKB;CALM3A;PIK3CD;DGKE |
IMPAD1 has several biochemical functions, for example, 3(2),5-bisphosphate nucleotidase activity, 3-nucleotidase activity, inositol monophosphate 1-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IMPAD1 itself. We selected most functions IMPAD1 had, and list some proteins which have the same functions with IMPAD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3(2),5-bisphosphate nucleotidase activity | IMPAD1;BPNT1 |
| 3-nucleotidase activity | |
| inositol monophosphate 1-phosphatase activity | IMPAD1;IMPA1;IMPA2 |
| inositol monophosphate 3-phosphatase activity | IMPAD1;IMPA2;IMPA1 |
| inositol monophosphate 4-phosphatase activity | IMPA1;IMPA2;IMPAD1 |
| magnesium ion binding | ADSS;ZAK;GLUL;ATP11A;PPM1AB;SRR;PPM1B;PRPS2;PPM1BB |
IMPAD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMPAD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IMPAD1.
- Q&As
- Reviews
Q&As (6)
Ask a questionThis is intracellular involved in the inositol metabolic pathway, which is a key process for intracellular signaling and maintenance of cell membrane structure.
It may play an important role in several diseases, including nervous system diseases, metabolic syndrome and cardiovascular diseases. However, the specific mechanism and regulatory mode of action need to be further studied.
It may be involved in neurotransmitter synthesis and regulation of neuronal function, which may explain its role in neurological diseases.
IMPAD1 mutations may negatively affect membrane structure and function because it is involved in the intracellular inositol metabolic pathway, which is one of the key components of the cell membrane.
There is no found IMPAD1 immediate relation between mutation and genetic diseases, however, mutations may be inositol metabolic pathways and cellular functions, have a negative impact.
The interacts with signaling pathways and molecules related to inositol metabolism, such as inositol, inositol phosphate, and inositol phosphate ester.
Customer Reviews (3)
Write a reviewStability is very good, even if it is stored for a long time, it will not affect its performance.
Catalytic activity is amazing, it can achieve efficient catalysis under mild conditions, and its mild nature is appreciated.
Anti-interference ability of Western blot is very strong, which can effectively resist the influence of endogenous interference factors and ensure the accuracy of experimental results.
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