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ITIH4

Official Full Name

inter-alpha-trypsin inhibitor heavy chain family, member 4
Overview

The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression of this gene has been detected only in liver, and it seems to be upregulated during surgical trauma. This gene is part of a cluster of similar genes on chromosome 3. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms

ITIH4; inter-alpha-trypsin inhibitor heavy chain family, member 4; inter alpha (globulin) inhibitor H4 (plasma Kallikrein sensitive glycoprotein) , ITIHL1; inter-alpha-trypsin inhibitor heavy chain H4; H4P; IHRP; plasma Kallikrein sensitive glycoprotein;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian cells
Yeast

Tag

Flag
His
His (Fc)
Avi
His|GST
His|T7
SUMO
Myc
DDK
Myc|DDK
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ITIH4-2344H	Recombinant Human ITIH4 Protein, His-tagged	E.coli	N-His	Ala683-Val928	Inquiry
Human	ITIH4-669HFL	Recombinant Full Length Human ITIH4 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	ITIH4-2642H	Recombinant Human ITIH4 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	ITIH4-1565H	Recombinant Human ITIH4 protein, His-tagged	E.coli	His	Lys273~Ala424 (Accession # Q14624)	Inquiry
Human	ITIH4-1221H-B	Recombinant Human ITIH4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	ITIH4-4393H	Recombinant Human ITIH4 protein, His-SUMO-tagged	E.coli	His-SUMO	689-930aa	Inquiry
Human	ITIH4-5759H	Recombinant Human ITIH4 protein, His-tagged	Yeast	His	689-930aa	Inquiry
Human	ITIH4-1221H	Recombinant Human ITIH4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Itih4-1566M	Recombinant Mouse Itih4 protein, His & T7-tagged	E.coli	His/T7	His721~Ile942 (Accession # A6X935)	Inquiry
Mouse	Itih4-3614M	Recombinant Mouse Itih4 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	Itih4-1567R	Recombinant Rat Itih4 protein, His & GST-tagged	E.coli	His/GST	Thr478~Val722	Inquiry

ITIH4 Related Articles
ITIH4 Related Research Area

ITIH4 involved in several pathways and played different roles in them. We selected most pathways ITIH4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ITIH4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ITIH4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ITIH4 itself. We selected most functions ITIH4 had, and list some proteins which have the same functions with ITIH4. You can find most of the proteins on our site.

Function	Related Protein

ITIH4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITIH4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITIH4.

Webber, J; Stone, TC; et al. Proteomics Analysis of Cancer Exosomes Using a Novel Modified Aptamer-based Array (SOMAscan(TM)) Platform*. MOLECULAR & CELLULAR PROTEOMICS 13:1050-1064(2014).

Pineiro, M; Lampreave, F; et al. Development and validation of an ELISA for the quantification of pig Major Acute phase Protein (Pig-MAP). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 127:228-234(2009).

Serine Proteases and Regulators